IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene SIGLEC7 Ensembl ENSG00000168995 Chromosome 19 Start 56337370 End 56348595
Description Sialic acid-binding Ig-like lectin 7 Precursor (Siglec-7)(QA79 membrane protein)(Adhesion inhibitory receptor molecule 1)(AIRM-1)(p75)(D-siglec)(CDw328)(CD328 antigen) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y286]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 10876
     Entrez Gene : 27036
     UCSC : uc002pvv.1
     GeneCards : 10876
     RefSeq : NM_014385
     CCDS : CCDS12826.1
     Uniprot : Q9Y286
     Interpro : Q9Y286
     OMIM : 604410
     GeneTests : SIGLEC7
     CGAP : SIGLEC7
     PMID : 10567377

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  34977_at  -0.06  7.75e-1  8.38e-1  -1.10  1.02e-3  3.15e-3
 HG_U95  34978_g_at  -0.13  3.11e-1  4.16e-1  -0.20  2.67e-1  3.67e-1
 HG_U133A  207224_s_at  -0.50  7.69e-9  2.45e-8  -2.74  5.75e-30  9.66e-30
 HG_U133A  216537_s_at  0.17  3.40e-2  4.87e-2  -0.71  4.15e-10  5.21e-10
 HG_U133A  217159_x_at  -0.25  5.23e-5  1.12e-4  -1.51  3.57e-27  5.76e-27
 HG_U133_Plus2  207224_s_at  -0.41  8.63e-4  2.27e-3  -0.53  9.36e-5  2.10e-4
 HG_U133_Plus2  216537_s_at  -0.10  4.32e-1  5.22e-1  -0.07  5.88e-1  6.43e-1
 HG_U133_Plus2  217159_x_at  -0.77  1.20e-6  5.33e-6  -0.72  4.51e-5  1.06e-4
 Stanford  16946  -1.06  4.54e-3  3.83e-2  -0.74  3.75e-2  1.39e-1
 Agilent_HS_21.6K  9153  -0.11  4.36e-5  6.02e-4  -0.13  1.53e-7  3.17e-6

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  207224_s_at  0.69  3.03e-2  6.99e-1  -0.14  4.67e-1  1.00e+0
 HG_U133A  216537_s_at  0.21  4.10e-1  9.05e-1  0.13  5.16e-1  1.00e+0
 HG_U133A  217159_x_at  0.12  5.89e-1  9.50e-1  -0.08  6.24e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 34977_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 34978_g_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 207224_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 216537_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 217159_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 207224_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 216537_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 217159_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 16946    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 9153    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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