IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene SIGLEC6 Ensembl ENSG00000105492 Chromosome 19 Start 56712763 End 56726922
Description Sialic acid-binding Ig-like lectin 6 Precursor (Siglec-6)(Obesity-binding protein 1)(OB-BP1)(CD33 antigen-like 1)(CDw327)(CD327 antigen) [Source:UniProtKB/Swiss-Prot;Acc:O43699]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 10875
     Entrez Gene : 946
     UCSC : uc002pwy.2
     GeneCards : 10875
     RefSeq : NM_001177547
     CCDS : CCDS12834.3
     Uniprot : O43699
     Interpro : O43699
     OMIM : 604405
     GeneTests : SIGLEC6
     CGAP : SIGLEC6
     PMID : 9465907

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  34483_at  -0.48  3.30e-2  6.49e-2  -0.99  1.05e-3  3.23e-3
 HG_U133A  206519_x_at  -0.54  3.62e-4  7.00e-4  1.19  9.55e-13  1.25e-12
 HG_U133A  206520_x_at  -0.14  1.51e-3  2.68e-3  -5.27  6.98e-53  1.66e-52
 HG_U133A  210796_x_at  -0.24  6.22e-7  1.64e-6  0.43  2.62e-6  3.08e-6
 HG_U133_Plus2  206519_x_at  -1.78  1.60e-16  2.58e-15  -2.35  1.22e-22  2.29e-21
 HG_U133_Plus2  206520_x_at  0.47  6.28e-5  2.07e-4  1.10  5.16e-14  3.61e-13
 HG_U133_Plus2  210796_x_at  0.18  1.26e-1  1.87e-1  0.76  2.74e-7  8.65e-7
 Agilent_HS_21.6K  20981  -0.05  6.10e-2  1.67e-1  -0.08  3.86e-2  1.02e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  206519_x_at  -0.75  1.19e-1  7.87e-1  -0.05  8.81e-1  1.00e+0
 HG_U133A  206520_x_at  -0.12  4.37e-1  9.13e-1  -0.01  9.45e-1  1.00e+0
 HG_U133A  210796_x_at  -0.11  5.50e-1  9.39e-1  0.03  7.73e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 34483_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 206519_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 206520_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 210796_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 206519_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 206520_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 210796_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 20981    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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