IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene PRPF31 Ensembl ENSG00000105618 Chromosome 19 Start 59310649 End 59326952
Description U4/U6 small nuclear ribonucleoprotein Prp31 (Pre-mRNA-processing factor 31)(U4/U6 snRNP 61 kDa protein)(hPrp31)(Protein 61K)(Serologically defined breast cancer antigen NY-BR-99) [Source:UniProtKB/Swiss-Prot;Acc:Q8WWY3]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 15446
     Entrez Gene : 26121
     UCSC : uc002qdh.2
     GeneCards : 15446
     RefSeq : NM_015629
     CCDS : CCDS12879.1
     Uniprot : Q8WWY3
     Interpro : Q8WWY3
     OMIM : 606419
     GeneTests : PRPF31
     CGAP : PRPF31
     PMID : 11545739

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  40905_s_at  -0.07  6.46e-1  7.32e-1  0.23  1.37e-1  2.13e-1
 HG_U133A  202407_s_at  1.08  6.85e-21  5.75e-20  2.75  1.02e-54  2.52e-54
 HG_U133A  202408_s_at  0.19  6.62e-4  1.24e-3  -1.05  9.13e-30  1.53e-29
 HG_U133A  214380_at  0.46  9.94e-5  2.07e-4  2.80  2.61e-49  5.88e-49
 HG_U133_Plus2  202407_s_at  0.23  8.09e-2  1.28e-1  0.51  2.04e-6  5.75e-6
 HG_U133_Plus2  202408_s_at  0.15  1.32e-2  2.62e-2  0.41  5.27e-7  1.60e-6
 HG_U133_Plus2  214380_at  0.27  4.24e-2  7.31e-2  0.36  2.25e-2  3.45e-2
 Agilent_HS_21.6K  19385  -0.03  5.19e-1  6.90e-1  0.02  7.48e-1  8.39e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  202407_s_at  -0.09  7.65e-1  9.75e-1  -0.44  1.86e-1  1.00e+0
 HG_U133A  202408_s_at  -0.33  4.84e-2  7.08e-1  0.08  5.91e-1  1.00e+0
 HG_U133A  214380_at  -0.11  6.73e-1  9.65e-1  0.34  1.52e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 40905_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 202407_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 202408_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 214380_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 202407_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 202408_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 214380_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 19385    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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