IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene CNOT3 Ensembl ENSG00000088038 Chromosome 19 Start 59333261 End 59351239
Description CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3)(Leukocyte receptor cluster member 2) [Source:UniProtKB/Swiss-Prot;Acc:O75175]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 7879
     Entrez Gene : 4849
     UCSC : uc002qdj.1
     GeneCards : 7879
     RefSeq : NM_014516
     CCDS : CCDS12880.1
     Uniprot : O75175
     Interpro : O75175
     OMIM : 604910
     GeneTests : CNOT3
     CGAP : CNOT3
     PMID : 10637334

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  38310_at  0.21  9.91e-3  2.32e-2  0.14  2.14e-1  3.07e-1
 HG_U133A  203239_s_at  0.54  1.63e-15  9.10e-15  5.21  2.32e-158  1.10e-156
 HG_U133A  211141_s_at  1.67  3.97e-29  5.83e-28  3.37  6.24e-70  2.03e-69
 HG_U133_Plus2  203239_s_at  0.57  2.05e-7  1.03e-6  1.27  3.38e-16  3.05e-15
 HG_U133_Plus2  211141_s_at  0.17  3.50e-1  4.39e-1  0.59  3.97e-3  6.93e-3
 HG_U133_Plus2  229143_at  0.34  4.45e-3  9.92e-3  0.48  3.88e-5  9.18e-5
 Stanford  9228  0.52  6.75e-2  1.90e-1  0.25  3.87e-1  6.24e-1
 Stanford  22245  -1.19  1.18e-2  7.17e-2  -1.92  9.75e-6  5.11e-4
 Agilent_HS_21.6K  5408  -0.05  3.19e-1  5.06e-1  0.01  8.82e-1  9.29e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  203239_s_at  -0.16  5.27e-1  9.34e-1  0.06  7.20e-1  1.00e+0
 HG_U133A  211141_s_at  -0.24  6.37e-1  9.59e-1  -0.40  2.31e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 38310_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 203239_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 211141_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 203239_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 211141_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 229143_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 9228    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 22245    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 5408    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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