IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene MBOAT7 Ensembl ENSG00000125505 Chromosome 19 Start 59368921 End 59385478
Description Membrane-bound O-acyltransferase domain-containing protein 7 (O-acyltransferase domain-containing protein 7)(EC 2.3.-.-)(Leukocyte receptor cluster member 4)(Bladder and breast carcinoma-overexpressed gene 1 protein) [Source:UniProtKB/Swiss-Prot;Acc:Q96N66]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 15505
     Entrez Gene : 79143
     UCSC : uc002qdr.2
     GeneCards : 15505
     RefSeq : NM_001146056
     CCDS : CCDS12883.1
     Uniprot : Q9BRE9
     Interpro : Q9BRE9
     OMIM : 606048
     GeneTests : MBOAT7
     CGAP : MBOAT7
     PMID : 10941842

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  180_at  0.90  6.19e-6  3.38e-5  0.49  5.61e-2  1.01e-1
 HG_U95  181_g_at  0.37  5.87e-5  2.54e-4  0.25  1.20e-2  2.70e-2
 HG_U133A  209179_s_at  0.44  2.26e-8  6.86e-8  2.56  8.15e-72  2.74e-71
 HG_U133A  211037_s_at  0.16  1.71e-1  2.13e-1  -2.19  5.61e-30  9.43e-30
 HG_U133_Plus2  209179_s_at  0.74  4.82e-12  4.54e-11  0.92  6.86e-11  3.35e-10
 HG_U133_Plus2  211037_s_at  0.21  1.77e-1  2.49e-1  -0.18  2.85e-1  3.43e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  209179_s_at  -0.02  9.50e-1  9.98e-1  0.04  8.75e-1  1.00e+0
 HG_U133A  211037_s_at  -0.24  4.94e-1  9.26e-1  0.28  2.92e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 180_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 181_g_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 209179_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 211037_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 209179_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 211037_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
bb1 breast carcinoma Molecular analysis of a gene, BB1, overexpressed in bladder and breast carcinoma. 8702217 Human
bb1 bladder carcinomas RNA analysis demonstrated increased expression of BB1 mRNA in metastatic breast and bladder carcinomas relative to normal breast epithelium and urothelium. 8702217 Human
bb1 tumor BB1 mRNA expression is increased in malignant cells relative to normal cells and is down-regulated following gamma-interferon treatment and therefore may have a role in tumor progression. 8702217 Human
bb1 breast carcinoma Expression of another five genes was decreased in W/W(V) mice: BB1 (overexpressed in bladder and breast carcinoma), HTATIP/CPLA2 (HIV-1 TAT interactive protein/cytosolic phospholipase A2), Tenascin-receptor like (Hexabrachion, Cytotactin, Neuronectin, Myo 15065000 Human

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