IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene LAIR2 Ensembl ENSG00000167618 Chromosome 19 Start 59705825 End 59713707
Description Leukocyte-associated immunoglobulin-like receptor 2 Precursor (LAIR-2)(CD306 antigen) [Source:UniProtKB/Swiss-Prot;Acc:Q6ISS4]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 6478
     Entrez Gene : 3904
     UCSC : uc002qgc.2
     GeneCards : 6478
     RefSeq : NM_002288
     CCDS : CCDS12897.1
     Uniprot : Q6ISS4
     Interpro : Q6ISS4
     OMIM : 602993
     GeneTests : LAIR2
     CGAP : LAIR2
     PMID : 9285412

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  33541_s_at  -0.57  8.18e-3  1.96e-2  -1.18  7.49e-5  3.07e-4
 HG_U133A  207509_s_at  -0.35  6.29e-4  1.18e-3  -2.95  2.58e-61  7.14e-61
 HG_U133_Plus2  207509_s_at  0.04  7.72e-1  8.25e-1  -0.41  7.30e-4  1.44e-3
 Agilent_HS_21.6K  20301  -0.16  2.53e-1  4.37e-1  -0.18  1.29e-1  2.50e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  207509_s_at  -0.09  6.73e-1  9.65e-1  0.05  7.57e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 33541_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 207509_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 207509_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 20301    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
lair-2 leukemia METHODS: Genes encoding LAIR-1 and LAIR-2 were cloned by RT-PCR from human peripheral blood mononuclear cells(PBMC) and two leukemia cell lines Jurkat and HL-60. 15151743 Human
lair-2 leukemia METHODS: Genes encoding LAIR-1 and LAIR-2 were cloned by RT-PCR from human peripheral blood mononuclear cells(PBMC) and two leukemia cell lines Jurkat and HL-60. 15151743 Human
lair-2 melanoma RESULTS: Both LAIR-1 and LAIR-2 fusion proteins bound strongly with human amnion-derived epithelial cell line WISH, and moderately with human melanoma cell line C32, human embryo kidney epithelial cell line 293T, and human umbilical vein endothelial cell 16143055 Human

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