IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene KIR3DL3 Ensembl ENSG00000221906 Chromosome 19 Start 59927796 End 59939815
Description killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 [Source:RefSeq peptide;Acc:NP_703144]

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  31780_f_at  0.02  8.93e-1  9.24e-1  0.14  4.65e-1  5.68e-1
 HG_U133A  216676_x_at  -0.37  1.25e-4  2.57e-4  -0.91  9.43e-11  1.20e-10
 HG_U133_Plus2  216676_x_at  -0.27  1.46e-1  2.12e-1  -0.08  6.49e-1  6.99e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  216676_x_at  0.18  3.98e-1  8.99e-1  0.13  4.93e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 31780_f_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 216676_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 216676_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
kir3dl3 cin An A-genotype including KIR2DL1, KIR2DL2, KIR2DL3, KIR2DL4, KIR3DL1, KIR3DL2, KIR3DL3, and KIR2DS4 was associated with increased risk of CIN (OR 6.7; 95% CI 1.7-26.3), and KIR2DL5B*002 appeared to have an inverse association with disease (OR 0.5; 95% CI 0 15730517 Human

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