IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene HSPBP1 Ensembl ENSG00000133265 Chromosome 19 Start 60465520 End 60483291
Description Hsp70-binding protein 1 (Heat shock protein-binding protein 1)(HspBP1)(Hsp70-interacting protein 1)(Hsp70-binding protein 2)(HspBP2)(Hsp70-interacting protein 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9NZL4]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 24989
     Entrez Gene : 23640
     UCSC : uc002qkd.2
     GeneCards : 24989
     RefSeq : NM_001130106
     CCDS : CCDS33111.1
     Uniprot : Q9NZL4
     Interpro : Q9NZL4
     OMIM : 612939
     GeneTests : HSPBP1
     CGAP : HSPBP1
     PMID : 10786638

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  35269_at  0.07  6.10e-1  7.01e-1  0.15  3.41e-1  4.47e-1
 HG_U133A  202415_s_at  0.62  2.39e-19  1.79e-18  2.68  1.15e-90  6.09e-90
 HG_U133_Plus2  202415_s_at  0.63  6.87e-12  6.32e-11  0.98  4.98e-15  3.91e-14
 Stanford  19236  0.70  8.76e-3  5.91e-2  0.68  2.20e-2  1.16e-1
 Agilent_HS_21.6K  9012  -0.08  2.73e-2  9.50e-2  -0.04  4.05e-1  5.65e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  202415_s_at  0.11  5.32e-1  9.35e-1  0.23  7.40e-2  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 35269_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 202415_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 202415_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 19236    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 9012    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
hspbp1 tumors Increased expression of the Hsp70 cochaperone HspBP1 in tumors. 15004487 Human
hspbp1 tumor The purpose of this study was to determine if the levels of HspBP1 are altered in tumor cells. 15004487 Human
hspbp1 tumors In this report, we show that HspBP1 levels are elevated in two mouse tumor models, 3LL cells (Lewis Lung carcinoma) and neuroblastoma tumors. 15004487 Human
hspbp1 mouse tumor In this report, we show that HspBP1 levels are elevated in two mouse tumor models, 3LL cells (Lewis Lung carcinoma) and neuroblastoma tumors. 15004487 Human
hspbp1 lewis lung carcinoma In this report, we show that HspBP1 levels are elevated in two mouse tumor models, 3LL cells (Lewis Lung carcinoma) and neuroblastoma tumors. 15004487 Human
hspbp1 neuroblastoma In this report, we show that HspBP1 levels are elevated in two mouse tumor models, 3LL cells (Lewis Lung carcinoma) and neuroblastoma tumors. 15004487 Human
hspbp1 tumors The amounts of HspBP1 and Hsp70 in selected tissues, tumors and a rabbit reticulocyte lysate were determined using Western blots. 15004487 Human
hspbp1 cancer These studies have shown that HspBP1 is elevated in the tumors examined and therefore could be a new cancer marker. 15004487 Human
hspbp1 tumors These studies have shown that HspBP1 is elevated in the tumors examined and therefore could be a new cancer marker. 15004487 Human

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