IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene U2AF2 Ensembl ENSG00000063244 Chromosome 19 Start 60857228 End 60877893
Description Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit)(hU2AF65)(hU2AF(65))(U2 snRNP auxiliary factor large subunit) [Source:UniProtKB/Swiss-Prot;Acc:P26368]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 23156
     Entrez Gene : 11338
     UCSC : uc002qlu.2
     GeneCards : 23156
     RefSeq : NM_001012478
     CCDS : CCDS12933.1
     Uniprot : P26368
     Interpro : P26368
     OMIM : 191318
     GeneTests : U2AF2
     CGAP : U2AF2
     PMID : 1538748

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  32556_at  0.62  3.47e-8  3.11e-7  0.93  1.35e-9  1.46e-8
 HG_U95  32557_at  0.30  2.60e-4  9.55e-4  0.46  7.98e-5  3.26e-4
 HG_U133A  214171_s_at  -0.02  8.91e-1  9.08e-1  -0.35  7.87e-4  8.80e-4
 HG_U133A  218381_s_at  0.51  7.72e-18  5.16e-17  0.51  2.75e-12  3.56e-12
 HG_U133A  218382_s_at  0.64  1.47e-14  7.68e-14  0.14  1.21e-1  1.27e-1
 HG_U133_Plus2  214171_s_at  0.16  2.85e-1  3.71e-1  -0.01  9.56e-1  9.65e-1
 HG_U133_Plus2  218381_s_at  0.66  1.68e-14  2.13e-13  1.17  6.80e-25  1.65e-23
 HG_U133_Plus2  218382_s_at  1.22  6.23e-14  7.44e-13  1.57  1.63e-12  9.70e-12
 HG_U133_Plus2  229508_at  -0.05  7.38e-1  7.97e-1  -0.10  4.53e-1  5.14e-1
 Agilent_HS_21.6K  2662  0.00  9.97e-1  9.99e-1  0.05  2.68e-1  4.22e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  214171_s_at  -0.16  6.02e-1  9.53e-1  0.11  6.61e-1  1.00e+0
 HG_U133A  218381_s_at  0.36  1.08e-1  7.80e-1  0.20  1.52e-1  1.00e+0
 HG_U133A  218382_s_at  0.08  7.48e-1  9.74e-1  -0.01  9.27e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 32556_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 32557_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 214171_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 218381_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 218382_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 214171_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 218381_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 218382_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 229508_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 2662    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
u2af2 polyp Eight candidate genes mapping to the breakpoint region--U2AF2, EPN1, NALP4, NALP11, NALP5, ZNF444, PTPRH, and KIAA1811--were screened for mutations in germ-line and polyp DNA from the case and from 15 PJS cases that did not harbor germ-line STK11 mutation 15287029 Human

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