IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene CHMP2A Ensembl ENSG00000130724 Chromosome 19 Start 63754746 End 63758298
Description Charged multivesicular body protein 2a (Chromatin-modifying protein 2a)(CHMP2a)(Vacuolar protein-sorting-associated protein 2-1)(Vps2-1)(hVps2-1)(Putative breast adenocarcinoma marker BC-2) [Source:UniProtKB/Swiss-Prot;Acc:O43633]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 30216
     Entrez Gene : 27243
     UCSC : uc002qtk.2
     GeneCards : 30216
     RefSeq : NM_014453
     CCDS : CCDS12986.1
     Uniprot : O43633
     Interpro : O43633
     OMIM : 610893
     GeneTests : CHMP2A
     CGAP : CHMP2A
     PMID : 15173323

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  39363_at  -0.14  8.34e-2  1.42e-1  -0.51  1.31e-8  1.19e-7
 HG_U133A  202121_s_at  0.22  1.83e-5  4.13e-5  -1.01  5.31e-37  9.85e-37
 HG_U133_Plus2  202121_s_at  -0.21  1.64e-3  4.05e-3  -0.55  2.74e-11  1.40e-10

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  202121_s_at  0.22  1.89e-1  8.25e-1  -0.26  9.22e-2  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 39363_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 202121_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 202121_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
bc-2 tumor At immunohistochemistry the tumor cells were diffusely positive for vimentin and CD34, but negatively stained with CD99, bc-2, desmin, smooth-muscle actin, S100 protein and cytokeratins. 12540995 Human
bc-2 tumor Demonstrating the advantage of this approach, new annotations are provided for two novel proteins: 1) a membrane-bound O-acyltransferase protein (C3F) that, when overexpressed, disrupts Golgi and endosome integrity due likely to an endoplasmic reticulum-G 15965266 Human

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