IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene CBLL1 Ensembl ENSG00000105879 Chromosome 7 Start 107171822 End 107187260
Description E3 ubiquitin-protein ligase Hakai (EC 6.3.2.-)(Casitas B-lineage lymphoma-transforming sequence-like protein 1)(c-Cbl-like protein 1)(RING finger protein 188) [Source:UniProtKB/Swiss-Prot;Acc:Q75N03]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 21225
     Entrez Gene : 79872
     UCSC : uc003veq.2
     GeneCards : 21225
     RefSeq : NM_024814
     CCDS : CCDS5747.1
     Uniprot : Q75N03
     Interpro : Q75N03
     OMIM : 606872
     GeneTests : CBLL1
     CGAP : CBLL1
     PMID : 11836526

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  220018_at  0.06  5.65e-1  6.14e-1  0.57  1.81e-3  2.00e-3
 HG_U133_Plus2  220018_at  -0.21  1.43e-1  2.08e-1  -0.06  6.56e-1  7.05e-1
 HG_U133_Plus2  227187_at  0.18  3.10e-2  5.55e-2  0.07  4.27e-1  4.88e-1
 Agilent_HS_21.6K  17470  0.10  7.80e-3  3.80e-2  0.13  4.64e-3  1.92e-2

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  220018_at  0.45  3.38e-1  8.87e-1  -0.10  7.19e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U133A - 220018_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 220018_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 227187_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 17470    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
hakai metastasis Through dynamic recycling of E-cadherin, Hakai can thus modulate cell adhesion, and could participate in the regulation of epithelial--mesenchymal transitions in development or metastasis. 11836526 Human

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