IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene CAPZA2 Ensembl ENSG00000198898 Chromosome 7 Start 116289799 End 116346548
Description F-actin-capping protein subunit alpha-2 (CapZ alpha-2) [Source:UniProtKB/Swiss-Prot;Acc:P47755]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :
     HGNC : 1490
     Entrez Gene : 830
     UCSC : uc003vil.2
     GeneCards : 1490
     RefSeq : NM_006136
     CCDS : CCDS5768.1
     Uniprot : P47755
     Interpro : P47755
     OMIM : 601571
     GeneTests : CAPZA2
     CGAP : CAPZA2

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  36641_at  -0.46  1.96e-10  2.80e-9  -0.76  3.68e-14  9.84e-13
 HG_U133A  201237_at  -0.41  1.14e-8  3.58e-8  1.69  9.95e-48  2.18e-47
 HG_U133A  201238_s_at  -0.22  6.38e-3  1.03e-2  0.20  7.15e-3  7.80e-3
 HG_U133_Plus2  1569450_at  -1.07  9.83e-7  4.45e-6  -1.96  4.22e-13  2.67e-12
 HG_U133_Plus2  201237_at  -0.24  1.44e-2  2.83e-2  -0.63  1.20e-7  3.96e-7
 HG_U133_Plus2  201238_s_at  -0.28  3.17e-3  7.34e-3  -0.85  7.58e-13  4.67e-12
 Stanford  15134  -1.40  4.68e-3  3.92e-2  -0.82  4.04e-2  1.47e-1
 Agilent_HS_21.6K  13207  0.09  2.91e-1  4.78e-1  0.03  6.91e-1  7.98e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  201237_at  -0.11  6.42e-1  9.59e-1  -0.01  9.56e-1  1.00e+0
 HG_U133A  201238_s_at  0.24  3.50e-1  8.89e-1  -0.15  4.95e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 36641_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 201237_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 201238_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 1569450_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 201237_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 201238_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 15134    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 13207    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
capza2 tumor Two newly identified exons and the CAPZA2 exons were amplified in tumor TX3095, which retains an amplified MET gene. 9402967 Human

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