IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene KCND2 Ensembl ENSG00000184408 Chromosome 7 Start 119701923 End 120177623
Description Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2) [Source:UniProtKB/Swiss-Prot;Acc:Q9NZV8]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 6238
     Entrez Gene : 3751
     UCSC : uc003vjj.1
     GeneCards : 6238
     RefSeq : NM_012281
     CCDS : CCDS5776.1
     Uniprot : Q9NZV8
     Interpro : Q9NZV8
     OMIM : 605410
     GeneTests : KCND2
     CGAP : KCND2
     PMID : 10551270

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  32873_at  0.41  5.35e-2  9.76e-2  0.06  8.25e-1  8.75e-1
 HG_U133A  207103_at  0.51  1.02e-3  1.85e-3  0.93  9.92e-11  1.26e-10
 HG_U133_Plus2  207103_at  0.66  7.87e-4  2.09e-3  0.39  8.29e-2  1.13e-1
 Agilent_HS_21.6K  11644  0.02  5.29e-1  6.98e-1  0.02  3.82e-1  5.43e-1
 Agilent_HS_21.6K  15115  0.09  4.24e-3  2.39e-2  0.10  1.08e-2  3.83e-2

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  207103_at  0.33  5.82e-1  9.49e-1  0.01  9.76e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 32873_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 207103_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 207103_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 11644    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 15115    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
kv4.2 ascites hepatoma Expression of both delayed rectifier (Kv1.1, Kv1.2, Kv1.3, Kv1.5, Kv1.6, Kv2.1, Kv3.1, Kv4.2) and A-type potassium channels (Kv1.4, Kv3.3, Kv3.4) was greatly down-regulated in brain from animals bearing a Yoshida AH-130 ascites hepatoma. 12586336 Rat

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