IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene FAM3C Ensembl ENSG00000196937 Chromosome 7 Start 120776143 End 120823658
Description Protein FAM3C Precursor [Source:UniProtKB/Swiss-Prot;Acc:Q92520]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 18664
     Entrez Gene : 10447
     UCSC : uc010lkm.2
     GeneCards : 18664
     RefSeq : NM_001040020
     CCDS : CCDS5782.1
     Uniprot : Q92520
     Interpro : Q92520
     OMIM : 608618
     GeneTests : FAM3C
     CGAP : FAM3C
     PMID : 12160727

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  34321_i_at  0.38  3.98e-2  7.62e-2  0.57  2.82e-2  5.64e-2
 HG_U95  34322_r_at  0.19  3.55e-1  4.62e-1  0.01  9.60e-1  9.73e-1
 HG_U133A  201889_at  0.79  6.67e-17  4.15e-16  0.90  7.07e-14  9.39e-14
 HG_U133_Plus2  201889_at  0.61  3.93e-8  2.21e-7  0.60  1.34e-9  5.66e-9
 HG_U133_Plus2  236316_at  0.92  1.07e-5  4.07e-5  0.49  3.92e-2  5.73e-2
 HG_U133_Plus2  240062_at  0.65  1.15e-5  4.34e-5  0.44  4.62e-3  7.98e-3
 Agilent_HS_21.6K  16177  0.41  6.37e-4  5.29e-3  0.48  2.79e-5  2.70e-4

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  201889_at  -0.37  2.51e-1  8.53e-1  -0.29  1.73e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 34321_i_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 34322_r_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 201889_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 201889_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 236316_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 240062_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 16177    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
fam3c pancreatic cancer In addition, we identified several proteins that have not been correlated previously with pancreatic cancer including perlecan (HSPG2), CD9 antigen, fibronectin receptor (integrin beta1), and a novel cytokine designated as predicted osteoblast protein (FA 16215274 Human
ilei melanoses Electron microscopy (EM) and electron-probe energy dispersive x-ray analysis have rectified these errors and have shown the following: in melanosis coli the pigment granules contain lipofuscin; in melanoses ilei the pigment granules may contain either sil 7571080 Human
ilei melanosis Electron microscopy (EM) and electron-probe energy dispersive x-ray analysis have rectified these errors and have shown the following: in melanosis coli the pigment granules contain lipofuscin; in melanoses ilei the pigment granules may contain either sil 7571080 Human
ilei melanosis coli Electron microscopy (EM) and electron-probe energy dispersive x-ray analysis have rectified these errors and have shown the following: in melanosis coli the pigment granules contain lipofuscin; in melanoses ilei the pigment granules may contain either sil 7571080 Human
ilei melanosis Melanosis (haemosiderosis) ilei. We report here a case of melanosis ilei where grossly visible greyish black pigmentation of the ileal mucosa was discovered at autopsy. 7820812 Human
ilei melanoses The nature of the pigment granules which occur in the various melanoses is discussed; their pattern of distribution in melanosis coli, melanosis ilei, melanosis duodeni and melanosis oesophagi is summarized and current knowledge of the aetiology and patho 7821887 Human
ilei melanosis The nature of the pigment granules which occur in the various melanoses is discussed; their pattern of distribution in melanosis coli, melanosis ilei, melanosis duodeni and melanosis oesophagi is summarized and current knowledge of the aetiology and patho 7821887 Human
ilei melanosis coli The nature of the pigment granules which occur in the various melanoses is discussed; their pattern of distribution in melanosis coli, melanosis ilei, melanosis duodeni and melanosis oesophagi is summarized and current knowledge of the aetiology and patho 7821887 Human
ilei melanosis Two cases of melanosis ilei were studied, in which grossly visible blackish pigmentation of the ileal mucosa was incidentally discovered at autopsy. 8406389 Human
ilei melanosis These data, plus results of past electron-probe X-ray analytic studies by us and others, leads us to conclude that the pigment granules in melanosis ilei contain exogenous material derived from inspired and ingested materials. 8406389 Human
ilei metastasis ILEI: a cytokine essential for EMT, tumor formation, and late events in metastasis in epithelial cells. 16959614 Human
ilei tumor ILEI: a cytokine essential for EMT, tumor formation, and late events in metastasis in epithelial cells. 16959614 Human
ilei metastasis Stable overexpression of ILEI in EpH4 and EpRas cells caused EMT, tumor growth, and metastasis, independent of TGFbeta-R signaling and enhanced by Bcl2. 16959614 Human
ilei tumor Stable overexpression of ILEI in EpH4 and EpRas cells caused EMT, tumor growth, and metastasis, independent of TGFbeta-R signaling and enhanced by Bcl2. 16959614 Human
ilei metastasis RNAi-mediated knockdown of ILEI in EpRas cells before and after EMT (EpRasXT) prevented and reverted TGFbeta-dependent EMT, also abrogating metastasis formation. 16959614 Human
ilei metastasis ILEI is overexpressed and/or altered in intracellular localization in multiple human tumors, an event strongly correlated to invasion/EMT, metastasis formation, and survival in human colon and breast cancer. 16959614 Human
ilei human tumors ILEI is overexpressed and/or altered in intracellular localization in multiple human tumors, an event strongly correlated to invasion/EMT, metastasis formation, and survival in human colon and breast cancer. 16959614 Human
ilei breast cancer ILEI is overexpressed and/or altered in intracellular localization in multiple human tumors, an event strongly correlated to invasion/EMT, metastasis formation, and survival in human colon and breast cancer. 16959614 Human
ilei metastasis Screening for genes mediating EMT and cancer metastasis, Waerner, Alacakaptan, and colleagues identified ILEI, a cytokine-like protein that plays an essential role in EMT, tumor growth, and late steps of metastasis. 17011482 Human
ilei tumor Screening for genes mediating EMT and cancer metastasis, Waerner, Alacakaptan, and colleagues identified ILEI, a cytokine-like protein that plays an essential role in EMT, tumor growth, and late steps of metastasis. 17011482 Human
ilei cancer Screening for genes mediating EMT and cancer metastasis, Waerner, Alacakaptan, and colleagues identified ILEI, a cytokine-like protein that plays an essential role in EMT, tumor growth, and late steps of metastasis. 17011482 Human

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