IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene AASS Ensembl ENSG00000008311 Chromosome 7 Start 121503423 End 121571504
Description Alpha-aminoadipic semialdehyde synthase, mitochondrial Precursor (LKR/SDH) [Includes Lysine ketoglutarate reductase(LKR)(LOR)(EC 1.5.1.8);Saccharopine dehydrogenase(SDH)(EC 1.5.1.9)] [Source:UniProtKB/Swiss-Prot;Acc:Q9UDR5]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 17366
     Entrez Gene : 10157
     UCSC : uc003vkb.2
     GeneCards : 17366
     RefSeq : NM_005763
     CCDS : CCDS5783.1
     Uniprot : Q9UDR5
     Interpro : Q9UDR5
     OMIM : 605113
     GeneTests : AASS
     CGAP : AASS
     PMID : 10775527

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  35870_at  -0.35  1.07e-1  1.75e-1  -0.48  8.71e-2  1.46e-1
 HG_U133A  210852_s_at  -0.22  1.49e-1  1.89e-1  -2.23  5.86e-37  1.09e-36
 HG_U133A  214829_at  -0.59  2.88e-4  5.63e-4  -1.63  9.02e-25  1.41e-24
 HG_U133_Plus2  210852_s_at  -0.50  7.93e-5  2.56e-4  -0.27  6.75e-2  9.41e-2
 HG_U133_Plus2  214829_at  -0.36  4.27e-2  7.34e-2  0.02  9.11e-1  9.29e-1
 Agilent_HS_21.6K  7376  0.00  9.91e-1  9.95e-1  0.09  3.97e-1  5.57e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  210852_s_at  0.32  6.17e-1  9.54e-1  -0.31  3.71e-1  1.00e+0
 HG_U133A  214829_at  0.09  8.99e-1  9.94e-1  0.79  4.76e-2  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 35870_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 210852_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 214829_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 210852_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 214829_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 7376    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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