IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene GRM8 Ensembl ENSG00000179603 Chromosome 7 Start 125865888 End 126680584
Description Metabotropic glutamate receptor 8 Precursor (mGluR8) [Source:UniProtKB/Swiss-Prot;Acc:O00222]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 4600
     Entrez Gene : 2918
     UCSC : uc003vlr.2
     GeneCards : 4600
     RefSeq : NM_000845
     CCDS : CCDS5794.1
     Uniprot : Q52M02
     Interpro : Q52M02
     OMIM : 601116
     GeneTests : GRM8
     CGAP : GRM8
     PMID : 8824806

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  34007_at  0.49  2.21e-2  4.61e-2  0.36  1.55e-1  2.37e-1
 HG_U133A  216255_s_at  -0.51  4.99e-6  1.20e-5  5.90  1.50e-113  1.49e-112
 HG_U133A  216256_at  -0.21  3.47e-2  4.96e-2  -1.28  6.96e-34  1.23e-33
 HG_U133A  216992_s_at  -0.18  2.90e-1  3.42e-1  0.64  1.08e-5  1.25e-5
 HG_U133_Plus2  216255_s_at  -0.22  2.66e-1  3.50e-1  -0.21  3.28e-1  3.88e-1
 HG_U133_Plus2  216256_at  0.55  2.48e-4  7.30e-4  0.92  2.76e-8  9.85e-8
 HG_U133_Plus2  216992_s_at  -0.01  9.76e-1  9.83e-1  -0.12  6.35e-1  6.86e-1
 Stanford  614  0.36  4.55e-1  6.44e-1  0.75  4.66e-2  1.62e-1
 Agilent_HS_21.6K  7344  0.02  3.85e-1  5.72e-1  0.02  4.88e-1  6.38e-1
 Agilent_HS_21.6K  19845  0.06  4.41e-2  1.33e-1  0.07  2.90e-2  8.19e-2

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  216255_s_at  0.27  5.15e-1  9.34e-1  0.06  8.38e-1  1.00e+0
 HG_U133A  216256_at  -0.06  8.54e-1  9.88e-1  -0.06  7.57e-1  1.00e+0
 HG_U133A  216992_s_at  -0.96  6.94e-2  7.32e-1  0.58  1.58e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 34007_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 216255_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 216256_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 216992_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 216255_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 216256_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 216992_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 614    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 7344    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 19845    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
mglur8 c6 glioma C6 glioma cells expressed mRNA for group II mGluR3, group III mGluR4, mGluR6, mGluR7 and mGluR8. 15686497 Rat

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