IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene TNS3 Ensembl ENSG00000136205 Chromosome 7 Start 47281277 End 47588216
Description Tensin-3 (Tumor endothelial marker 6)(Tensin-like SH2 domain-containing protein 1) [Source:UniProtKB/Swiss-Prot;Acc:Q68CZ2]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 21616
     Entrez Gene : 64759
     UCSC : uc003tnv.2
     GeneCards : 21616
     RefSeq : NM_022748
     CCDS : CCDS5506.2
     Uniprot : Q68CZ2
     Interpro : Q68CZ2
     OMIM : 606825
     GeneTests : TNS3
     CGAP : TNS3
     PMID : 11559528

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  217853_at  -1.08  5.60e-45  2.14e-43  -3.53  3.14e-111  2.91e-110
 HG_U133_Plus2  217853_at  -0.68  6.32e-18  1.20e-16  -1.45  1.44e-23  3.04e-22
 HG_U133_Plus2  234257_at  0.44  2.09e-2  3.92e-2  0.67  1.82e-3  3.35e-3

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  217853_at  0.23  3.08e-1  8.77e-1  -0.20  4.94e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U133A - 217853_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 217853_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 234257_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
tem-6 breast cancer In addition, elevated levels of TEM-4, TEM-5, TEM-6, TEM-7 and TEM-7R were also raised in breast cancer tissues. 15065600 Human
tem-6 tumor The expressions of TEM-2 and TEM-6 were found to be not significantly different between tumor tissues and normal tissues (P > 0.05). 15761964 Human
tem-6 colorectal cancer CONCLUSION: The level of the expression of TEM-1, TEM-7, TEM-7R and TEM-8 (but not TEM-2 and TEM-6) were associated with both nodal involvement and disease progression, and may therefore, have a prognostic value in colorectal cancer. 15761964 Human

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