IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene LANCL2 Ensembl ENSG00000132434 Chromosome 7 Start 55400635 End 55468929
Description LanC-like protein 2 (Testis-specific adriamycin sensitivity protein) [Source:UniProtKB/Swiss-Prot;Acc:Q9NS86]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 6509
     Entrez Gene : 55915
     UCSC : uc003tqp.2
     GeneCards : 6509
     RefSeq : NM_018697
     CCDS : CCDS5517.1
     Uniprot : Q9NS86
     Interpro : Q9NS86
     OMIM : 612919
     GeneTests : LANCL2
     CGAP : LANCL2
     PMID : 11762191

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  218219_s_at  0.45  9.01e-10  3.15e-9  1.22  1.82e-41  3.61e-41
 HG_U133_Plus2  218219_s_at  0.28  1.39e-3  3.49e-3  0.57  2.48e-6  6.88e-6
 HG_U133_Plus2  222560_at  -0.02  9.25e-1  9.45e-1  0.14  4.85e-1  5.45e-1
 HG_U133_Plus2  222561_at  -0.29  1.09e-4  3.42e-4  -0.11  1.96e-1  2.47e-1
 Agilent_HS_21.6K  8285  0.03  7.06e-1  8.25e-1  0.12  1.20e-1  2.37e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  218219_s_at  0.19  4.33e-1  9.12e-1  -0.06  7.34e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U133A - 218219_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 218219_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 222560_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 222561_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 8285    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
lancl-2 human tumors With respect to this study, our data indicate that LanCl-2 increases cellular sensitivity to Adriamycin by decreasing the expression of P-gp, but more generally, these results indicate that the identification of bystander gene amplification in human tumor 12566319 Human
lancl2 glioblastomas LANCL2 (LANC-like 2) is a bystander gene that is coamplified and overexpressed with epidermal growth factor receptor in approximately 20% of all glioblastomas. 12566319 Human

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