IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene PSPH Ensembl ENSG00000146733 Chromosome 7 Start 56046240 End 56086762
Description Phosphoserine phosphatase (PSPase)(PSP)(EC 3.1.3.3)(O-phosphoserine phosphohydrolase)(L-3-phosphoserine phosphatase) [Source:UniProtKB/Swiss-Prot;Acc:P78330]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 9577
     Entrez Gene : 5723
     UCSC : uc003trh.2
     GeneCards : 9577
     RefSeq : NM_004577
     CCDS : CCDS5522.1
     Uniprot : P78330
     Interpro : P78330
     OMIM : 172480
     GeneTests : PSPH
     CGAP : PSPH
     PMID : 6297854

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  36736_f_at  0.80  5.67e-3  1.43e-2  1.30  4.83e-4  1.63e-3
 HG_U95  37209_g_at  0.95  1.14e-2  2.62e-2  1.54  1.47e-3  4.33e-3
 HG_U133A  205048_s_at  0.98  5.00e-4  9.50e-4  1.69  2.85e-7  3.40e-7
 HG_U133A  205194_at  0.96  4.71e-18  3.20e-17  2.32  1.98e-45  4.17e-45
 HG_U133_Plus2  205048_s_at  0.93  3.36e-3  7.73e-3  1.61  8.38e-6  2.17e-5
 HG_U133_Plus2  205194_at  1.10  5.85e-20  1.37e-18  1.79  5.61e-20  7.73e-19
 HG_U133_Plus2  244819_x_at  1.11  1.86e-7  9.46e-7  1.28  7.23e-7  2.16e-6
 Stanford  23775  0.70  2.26e-2  1.09e-1  0.98  2.83e-3  2.87e-2
 Agilent_HS_21.6K  12823  0.33  9.74e-3  4.50e-2  0.35  1.91e-2  5.95e-2

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  205048_s_at  0.35  7.28e-1  9.72e-1  0.32  5.20e-1  1.00e+0
 HG_U133A  205194_at  0.36  3.35e-1  8.87e-1  0.21  3.03e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 36736_f_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 37209_g_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 205048_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 205194_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 205048_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 205194_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 244819_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 23775    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 12823    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
phosphoserine phosphatase carcinomas The quantitative correlation of thymidine kinase (TK), uridine kinase (UK), and phosphoserine phosphatase to mitotic frequency was highly significant for mesotheliomas, as well as for carcinomas. 2882044 Human
phosphoserine phosphatase tumors Gene expression analysis reveals that both whole tumors and tumor-derived neurospheres express many genes characteristic of neural and other stem cells, including CD133, Sox2, musashi-1, bmi-1, maternal embryonic leucine zipper kinase, and phosphoserine p 14645703 Human
phosphoserine phosphatase colonic adenocarcinomas In samples of colonic adenocarcinomas, the mean activities of thymidine kinase, glucose-6-phosphate dehydrogenase, phosphoserine phosphatase and pyrroline-5-carboxylate reductase were several fold higher than those of nonneoplastic colon. 212173 Human
psph prostatic carcinoma The practical application of commercially available immunoperoxidase kits for prostatic specific antigen (PSA) and prostatic specific acid phosphatase (PSPH) were blindly evaluated on routinely formalin fixed and paraffin embedded tissue from 95 consecuti 2421532 Human
psph metastases The practical application of commercially available immunoperoxidase kits for prostatic specific antigen (PSA) and prostatic specific acid phosphatase (PSPH) were blindly evaluated on routinely formalin fixed and paraffin embedded tissue from 95 consecuti 2421532 Human
l-3-phosphoserine phosphatase gastric cancer Combination of L-3-phosphoserine phosphatase and CEA using real-time RT-PCR improves accuracy in detection of peritoneal micrometastasis of gastric cancer. 15154633 Human
phosphoserine phosphatase tumors The distribution among the different tumors of thymidine kinase, uridine kinase, phosphoserine phosphatase, hexokinase and adenylate kinase was found to correlate with each other. 6277448 Human
phosphoserine phosphatase mesotheliomas The quantitative correlation of thymidine kinase (TK), uridine kinase (UK), and phosphoserine phosphatase to mitotic frequency was highly significant for mesotheliomas, as well as for carcinomas. 2882044 Human
phosphoserine phosphatase myeloproliferative disorders Evidence for gene dosage effect for beta-glucuronidase (GUSB) and phosphoserine phosphatase (PSP), whose genes are mapped on chromosome 7, was searched in a group of 13 patients with myeloproliferative disorders and acquired monosomy 7. 1964582 Human

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