IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene TMEFF1 Ensembl ENSG00000066697 Chromosome 9 Start 102229380 End 102379733
Description Tomoregulin-1 Precursor (Transmembrane protein with EGF-like and one follistatin-like domain)(TR-1)(H7365) [Source:UniProtKB/Swiss-Prot;Acc:Q8IYR6]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :
     HGNC : 23370
     Entrez Gene : 91283
     GeneCards : 23370
     RefSeq : NM_080655
     CCDS : CCDS6749.1
     Uniprot : Q96H12
     Interpro : Q96H12
     GeneTests : C9orf30
     CGAP : C9orf30

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  37258_at  -0.34  2.28e-1  3.25e-1  -0.28  4.62e-1  5.66e-1
 HG_U133A  205122_at  0.38  1.12e-2  1.73e-2  -1.47  3.39e-23  5.15e-23
 HG_U133A  205123_s_at  0.20  1.39e-1  1.76e-1  -0.50  9.37e-4  1.04e-3
 HG_U133_Plus2  205122_at  -0.13  4.81e-1  5.69e-1  0.37  5.96e-2  8.41e-2
 HG_U133_Plus2  205123_s_at  -0.38  1.05e-1  1.60e-1  0.28  2.75e-1  3.33e-1
 Stanford  12901  0.51  3.26e-1  5.28e-1  0.90  9.22e-3  6.51e-2
 Agilent_HS_21.6K  4478  0.09  9.05e-2  2.20e-1  0.11  4.11e-2  1.07e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  205122_at  0.32  6.19e-1  9.54e-1  0.09  7.87e-1  1.00e+0
 HG_U133A  205123_s_at  0.88  3.48e-2  7.07e-1  -0.18  5.44e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 37258_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 205122_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 205123_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 205122_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 205123_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 12901    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 4478    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
tmeff1 brain tumors TMEFF1 and brain tumors. 12743596 Human
tmeff1 cancer Study of cancer cell lines from different tissues including the brain, demonstrated moderate to low levels of TMEFF1 in most of these transformed cell lines. 12743596 Human
tmeff1 tumors Furthermore, quantitative real-time RT-PCR analysis of 54 brain tumors showed that most of these tumors (96%) had lower levels of TMEFF1 expression than normal brain tissue. 12743596 Human
tmeff1 brain tumors Furthermore, quantitative real-time RT-PCR analysis of 54 brain tumors showed that most of these tumors (96%) had lower levels of TMEFF1 expression than normal brain tissue. 12743596 Human
tmeff1 brain cancer Interestingly, ectopic expression of TMEFF1 in brain cancer cells resulted in their growth inhibition. 12743596 Human
tmeff1 brain cancers These data suggest that TMEFF1 may behave as a tumor suppressor gene in brain cancers. 12743596 Human
tmeff1 tumor These data suggest that TMEFF1 may behave as a tumor suppressor gene in brain cancers. 12743596 Human

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