IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene POLE3 Ensembl ENSG00000148229 Chromosome 9 Start 115209342 End 115212773
Description DNA polymerase epsilon subunit 3 (DNA polymerase II subunit 3)(EC 2.7.7.7)(DNA polymerase epsilon subunit p17)(Chromatin accessibility complex 17)(HuCHRAC17)(CHRAC-17)(Arsenic-transactivated protein)(AsTP) [Source:UniProtKB/Swiss-Prot;Acc:Q9NRF9]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 13546
     Entrez Gene : 54107
     UCSC : uc004bhn.2
     GeneCards : 13546
     RefSeq : NM_017443
     CCDS : CCDS6795.1
     Uniprot : Q9NRF9
     Interpro : Q9NRF9
     OMIM : 607267
     GeneTests : POLE3
     CGAP : POLE3
     PMID : 10801849

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  38702_at  0.04  5.80e-1  6.75e-1  0.56  3.15e-8  2.64e-7
 HG_U133A  208828_at  0.32  2.55e-9  8.52e-9  -3.94  1.34e-106  1.09e-105
 HG_U133_Plus2  208828_at  0.54  5.15e-11  4.24e-10  1.23  8.39e-30  3.77e-28
 Stanford  1320  0.59  2.23e-2  1.08e-1  1.17  1.24e-3  1.62e-2
 Agilent_HS_21.6K  18992  -0.03  7.05e-1  8.25e-1  0.14  5.70e-2  1.36e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  208828_at  0.08  7.23e-1  9.72e-1  0.02  9.15e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 38702_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 208828_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 208828_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 1320    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 18992    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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