IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene ORM1 Ensembl ENSG00000187681 Chromosome 9 Start 116125119 End 116128458
Description Alpha-1-acid glycoprotein 1 Precursor (AGP 1)(Orosomucoid-1)(OMD 1) [Source:UniProtKB/Swiss-Prot;Acc:P02763]

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  205040_at  0.71  5.04e-3  8.27e-3  1.90  3.88e-31  6.62e-31
 HG_U133A  205041_s_at  0.33  1.78e-1  2.20e-1  1.47  4.91e-28  8.01e-28
 HG_U133A  214465_at  0.29  1.55e-1  1.95e-1  2.31  7.26e-49  1.62e-48
 HG_U133_Plus2  205040_at  -0.93  1.94e-4  5.84e-4  -2.14  1.03e-17  1.10e-16
 HG_U133_Plus2  205041_s_at  -0.78  4.03e-3  9.09e-3  -2.52  2.77e-17  2.83e-16
 HG_U133_Plus2  214465_at  -0.49  4.76e-2  8.07e-2  -2.11  8.27e-17  8.00e-16
 Agilent_HS_21.6K  1962  -0.08  3.72e-1  5.59e-1  -0.19  1.93e-3  9.33e-3

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  205040_at  -1.57  2.54e-2  6.98e-1  -0.17  7.25e-1  1.00e+0
 HG_U133A  205041_s_at  -0.96  1.23e-1  7.93e-1  -0.36  4.99e-1  1.00e+0
 HG_U133A  214465_at  -0.18  7.34e-1  9.73e-1  -0.17  5.81e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U133A - 205040_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 205041_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 214465_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 205040_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 205041_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 214465_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 1962    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
agp-a hepatoma The major component of human alpha 1-acid glycoprotein found in plasma is coded by AGP-A, which is expressed in liver and in hepatoma cell lines and is induced by inflammatory stimuli. 3360326 Human
orm tumor Previous investigations have suggested that ORM and other acute-phase reactants may act as blocking factors protecting tumor cells against immunological attack, thereby contributing to the 'immune escape' of the tumor. 7478438 Human
orm carcinoma of the breast ORM types were studied by isoelectric focusing and immunoprinting in patients with carcinoma of the breast, lung, ovary and endometrium and in population controls. 7478438 Human
orm1 carcinomas In accordance with a previous study, the frequencies of the ORM1*2 allele and the ORM1 2 phenotype were found to be significantly increased in patients with different types of carcinomas. 7478438 Human
orm1 cancer The results suggest that the ORM1 2 variant may influence the progression of cancer by being more immunosuppressive than the ORM1 1 variant. 7478438 Human
orm1 carcinoma The relative risk for carcinoma in patients with the ORM1 2 type was 1.56 (95% confidence interval:1.16-2.09). 7478438 Human
orm1 carcinomas In previous studies of orosomucoid (ORM) types and disease the ORM1 1 type has been found to be associated with sarcoidosis and other immunogenetic diseases, and the ORM 1 2 type with different types of carcinomas. 7576721 Human
orm carcinomas In previous studies of orosomucoid (ORM) types and disease the ORM1 1 type has been found to be associated with sarcoidosis and other immunogenetic diseases, and the ORM 1 2 type with different types of carcinomas. 7576721 Human
orm 1 carcinomas In previous studies of orosomucoid (ORM) types and disease the ORM1 1 type has been found to be associated with sarcoidosis and other immunogenetic diseases, and the ORM 1 2 type with different types of carcinomas. 7576721 Human
orm1 breast cancer We report significant associations between ORM1 and C3 types in sarcoidosis and breast cancer, but not in healthy individuals. 7576721 Human
orm1 breast cancer The ORM1 1 and C3S variants in combination increased the risk of sarcoidosis, and the ORM1 2 and C3F variants together gave an increased risk of breast cancer. 7576721 Human
orm1 carcinoma To investigate the relationship between ORM1 gene products and the development of carcinoma, we analyzed the ORM1 phenotypes of desialated sera from 125 patients with carcinoma. 1459112 Human
orm1 carcinoma In comparison to healthy individuals from the same geographical area [6] the ORM1 S phenotypes are significantly more frequent in carcinoma patients. 1459112 Human
agp-a hepatoma Using Hep3B hepatoma cells as a model system for the in vitro study of the acute phase reaction, we show that only AGP-A is strongly induced by treatment with culture medium of LPS stimulated monocytes. 2822385 Human
orm bladder cancer Performing 2-DE with subsequent MS analyses, conventional immunoblotting and immunohistochemistry we identified two proteins, orosomucoid (ORM) and human zinc-alpha(2)-glycoprotein (ZAG), which were increased in the urine samples of patients with bladder 16196100 Human
orm tumor Immunohistochemical studies showed ORM in inflammatory cells but also in endothelial cells of blood vessels within or adjacent to the tumor area and in part of the tumor cells. 16196100 Human

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