IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene TRIM32 Ensembl ENSG00000119401 Chromosome 9 Start 118489430 End 118503400
Description Tripartite motif-containing protein 32 (EC 6.3.2.-)(Zinc finger protein HT2A)(72 kDa Tat-interacting protein) [Source:UniProtKB/Swiss-Prot;Acc:Q13049]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 16380
     Entrez Gene : 22954
     UCSC : uc004bjw.2
     GeneCards : 16380
     RefSeq : NM_001099679
     CCDS : CCDS6817.1
     Uniprot : Q13049
     Interpro : Q13049
     OMIM : 602290
     GeneTests : TRIM32
     CGAP : TRIM32
     PMID : 11331580

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  38537_at  0.19  1.70e-1  2.56e-1  0.21  2.96e-1  3.98e-1
 HG_U133A  203846_at  -0.01  7.75e-1  8.08e-1  -0.23  1.19e-3  1.33e-3
 HG_U133_Plus2  203846_at  0.32  6.47e-7  3.02e-6  0.60  1.30e-11  6.91e-11
 HG_U133_Plus2  236233_at  0.12  1.87e-1  2.61e-1  0.06  6.07e-1  6.60e-1
 Stanford  22686  0.49  9.95e-3  6.45e-2  0.73  1.39e-2  8.66e-2
 Agilent_HS_21.6K  6140  -0.01  5.34e-1  7.01e-1  -0.02  4.31e-1  5.89e-1
 Agilent_HS_21.6K  12527  0.05  3.18e-2  1.06e-1  0.06  7.13e-2  1.61e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  203846_at  0.13  4.48e-1  9.14e-1  -0.18  2.09e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 38537_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 203846_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 203846_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 236233_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 22686    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 6140    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 12527    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
trim32 squamous cell carcinomas (scc) Tripartite motif protein 32, Trim32, mRNA and protein expression was elevated in independently transformed and tumorigenic keratinocytes of a mouse epidermal carcinogenesis model, in ultraviolet B (UVB)-induced squamous cell carcinomas (SCC), and in appro 14578165 Mouse
trim32 papillomas Tripartite motif protein 32, Trim32, mRNA and protein expression was elevated in independently transformed and tumorigenic keratinocytes of a mouse epidermal carcinogenesis model, in ultraviolet B (UVB)-induced squamous cell carcinomas (SCC), and in appro 14578165 Mouse
trim32 cancer This suggests that elevated Trim32 expression occurs frequently in experimental epidermal carcinogenesis and is relevant to human cancer. 14578165 Human

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