IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene CDK5RAP2 Ensembl ENSG00000136861 Chromosome 9 Start 122190968 End 122382258
Description CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48)(Centrosome-associated protein 215) [Source:UniProtKB/Swiss-Prot;Acc:Q96SN8]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 18672
     Entrez Gene : 55755
     UCSC : uc004bkf.2
     GeneCards : 18672
     RefSeq : NM_001011649
     CCDS : CCDS6823.1
     Uniprot : Q9NV90
     Interpro : Q9NV90
     OMIM : 608201
     GeneTests : CDK5RAP2
     CGAP : CDK5RAP2
     PMID : 10721722

< Top >


Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  220935_s_at  -0.24  2.76e-2  4.02e-2  1.10  5.05e-45  1.06e-44
 HG_U133_Plus2  220935_s_at  -0.01  9.60e-1  9.72e-1  0.70  3.26e-6  8.92e-6
 HG_U133_Plus2  233540_s_at  -0.16  9.90e-2  1.52e-1  0.33  2.14e-2  3.28e-2
 HG_U133_Plus2  237418_at  0.35  1.74e-2  3.34e-2  0.57  2.64e-4  5.56e-4
 HG_U133_Plus2  243153_at  -0.10  6.28e-1  7.04e-1  -0.42  1.13e-2  1.82e-2
 Agilent_HS_21.6K  19059  -0.04  5.14e-1  6.86e-1  0.27  1.79e-1  3.17e-1

< Top >


Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  220935_s_at  1.15  2.03e-2  6.83e-1  -0.23  5.93e-1  1.00e+0

< Top >


Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U133A - 220935_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 220935_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 233540_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 237418_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 243153_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 19059    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

< Top >


Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
cdk5rap2 chronic eosinophilic leukemia Transient response to imatinib in a chronic eosinophilic leukemia associated with ins(9;4)(q33;q12q25) and a CDK5RAP2-PDGFRA fusion gene. 16845659 Human
cdk5rap2 acute myeloid leukemia Despite achieving complete cytogenetic and molecular remission on imatinib, the patient relapsed with imatinib-resistant acute myeloid leukemia that was characterized by a normal karyotype, absence of detectable CDK5RAP2-PDGFRA mRNA, and a newly acquired 16845659 Human

< Top >


Download all image files.
Save all PNG files.    Save all PDF files.    Save all PS files.