IGDB.NSCLC Gene View
Gene Information Microarray Gene Expression Result Treatment Result Microarray Sample Data
 
Gene Information        (help)
Gene TYRP1 Ensembl ENSG00000107165 Chromosome 9 Start 12683435 End 12700290
Description 5,6-dihydroxyindole-2-carboxylic acid oxidase Precursor (DHICA oxidase)(EC 1.14.18.-)(Tyrosinase-related protein 1)(TRP-1)(TRP1)(TRP)(Catalase B)(Glycoprotein 75)(Melanoma antigen gp75) [Source:UniProtKB/Swiss-Prot;Acc:P17643]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 12450
     Entrez Gene : 7306
     UCSC : uc003zkv.3
     GeneCards : 12450
     RefSeq : NM_000550
     CCDS : CCDS34990.1
     Uniprot : P17643
     Interpro : P17643
     OMIM : 115501
     GeneTests : TYRP1
     CGAP : TYRP1
     PMID : 9434945

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  36911_at  -0.54  1.56e-2  3.42e-2  -0.51  1.07e-1  1.74e-1
 HG_U133A  205694_at  -1.13  1.32e-18  9.36e-18  -3.06  2.32e-70  7.59e-70
 HG_U133_Plus2  205694_at  -1.82  4.05e-20  9.64e-19  -1.90  1.37e-21  2.26e-20
 Stanford  157  -2.27  2.88e-5  1.45e-3  -1.96  8.09e-3  5.95e-2
 Agilent_HS_21.6K  439  -0.02  2.17e-1  3.94e-1  -0.03  1.52e-1  2.82e-1
 Agilent_HS_21.6K  16449  -0.31  7.43e-5  9.38e-4  -0.40  1.83e-9  7.16e-8

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  205694_at  0.63  1.51e-1  8.10e-1  0.13  5.39e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 36911_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 205694_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 205694_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 157    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 439    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 16449    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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