IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene PPP6C Ensembl ENSG00000119414 Chromosome 9 Start 126951230 End 126991886
Description Serine/threonine-protein phosphatase 6 catalytic subunit (PP6C)(EC 3.1.3.16) [Source:UniProtKB/Swiss-Prot;Acc:O00743]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 9323
     Entrez Gene : 5537
     UCSC : uc004bpg.3
     GeneCards : 9323
     RefSeq : NM_001123355
     CCDS : CCDS6861.1
     Uniprot : O00743
     Interpro : O00743
     OMIM : 612725
     GeneTests : PPP6C
     CGAP : PPP6C
     PMID : 9143513

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  37581_at  -0.36  1.29e-4  5.14e-4  -0.06  5.66e-1  6.61e-1
 HG_U133A  203529_at  -0.09  6.13e-2  8.38e-2  -4.91  3.26e-119  3.86e-118
 HG_U133A  206174_s_at  -0.07  1.33e-1  1.69e-1  -0.85  9.57e-32  1.64e-31
 HG_U133_Plus2  203529_at  -0.10  9.49e-2  1.46e-1  0.11  5.74e-2  8.12e-2
 HG_U133_Plus2  206174_s_at  0.05  4.93e-1  5.81e-1  0.42  1.02e-7  3.38e-7
 HG_U133_Plus2  225426_at  -0.74  1.62e-23  5.53e-22  -0.76  1.25e-17  1.33e-16
 HG_U133_Plus2  225429_at  -1.00  1.50e-31  1.24e-29  -1.16  3.80e-29  1.57e-27
 Stanford  3852  -0.04  8.26e-1  9.04e-1  0.06  7.64e-1  8.87e-1
 Agilent_HS_21.6K  7564  -0.12  3.87e-5  5.43e-4  -0.12  2.36e-3  1.10e-2

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  203529_at  0.22  2.82e-1  8.69e-1  0.02  8.92e-1  1.00e+0
 HG_U133A  206174_s_at  0.26  1.64e-1  8.15e-1  -0.12  4.43e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 37581_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 203529_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 206174_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 203529_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 206174_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 225426_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 225429_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 3852    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 7564    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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