IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene SH2D3C Ensembl ENSG00000095370 Chromosome 9 Start 129540419 End 129580740
Description SH2 domain-containing protein 3C (Novel SH2-containing protein 3) [Source:UniProtKB/Swiss-Prot;Acc:Q8N5H7]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 16884
     Entrez Gene : 10044
     UCSC : uc004bsc.2
     GeneCards : 16884
     RefSeq : NM_001142531
     CCDS : CCDS6877.1
     Uniprot : Q8N5H7
     Interpro : Q8N5H7
     OMIM : 604722
     GeneTests : SH2D3C
     CGAP : SH2D3C
     PMID : 10187783

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  215639_at  -0.13  1.27e-1  1.63e-1  -1.20  1.23e-23  1.88e-23
 HG_U133_Plus2  1552667_a_at  -1.70  1.29e-23  4.44e-22  -2.15  6.82e-20  9.31e-19
 HG_U133_Plus2  215639_at  -0.33  5.82e-2  9.61e-2  -0.22  2.29e-1  2.83e-1
 HG_U133_Plus2  226673_at  -1.99  1.44e-37  2.31e-35  -2.10  5.67e-30  2.62e-28
 Agilent_HS_21.6K  19167  -0.49  5.01e-19  2.35e-16  -0.50  8.77e-16  2.43e-13

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  215639_at  -0.01  9.65e-1  9.98e-1  -0.02  9.33e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U133A - 215639_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 1552667_a_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 215639_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 226673_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 19167    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
nsp3 stomach cancer Among the identified proteins, there were seven over-expressed proteins in stomach cancer tissue: NSP3, transgelin, prohibitin, heat shock protein (hsp) 27 and variant, protein disulfide isomerase A3, unnamed protein product and glucose regulated protein. 12923326 Human

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