IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene ST6GALNAC6 Ensembl ENSG00000160408 Chromosome 9 Start 129687421 End 129701753
Description Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 (EC 2.4.99.-)(GalNAc alpha-2,6-sialyltransferase VI)(hST6GalNAc VI)(ST6GalNAc VI)(Sialyltransferase 7F) [Source:UniProtKB/Swiss-Prot;Acc:Q969X2]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 23364
     Entrez Gene : 30815
     UCSC : uc004bso.1
     GeneCards : 23364
     RefSeq : NM_013443
     CCDS : CCDS6882.1
     Uniprot : Q969X2
     Interpro : Q969X2
     OMIM : 610135
     GeneTests : ST6GALNAC6
     CGAP : ST6GALNAC6
     PMID : 12668675

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133_Plus2  222571_at  -0.76  4.17e-11  3.48e-10  -1.07  5.39e-11  2.67e-10

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U133_Plus2 - 222571_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
st6galnac-vi renal cancer ST6GalNAc-VI and DSGG were found in proximal tubule epithelial cells in normal kidney tissues, while they were downregulated in renal cancer cell lines and cancer tissues. 17123352 Human
st6galnac-vi renal cancer Although both ST6GalNAc III and VI genes were expressed in normal kidney cells, the expression profiles of ST6GalNAc VI among 20 renal cancer cell lines correlated clearly with those of DSGG, suggesting that the sialyltransferase involved in the synthesis 17123352 Human
st6galnac-vi cancer ST6GalNAc-VI and DSGG were found in proximal tubule epithelial cells in normal kidney tissues, while they were downregulated in renal cancer cell lines and cancer tissues. 17123352 Human

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