IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene DOLK Ensembl ENSG00000175283 Chromosome 9 Start 130747630 End 130749719
Description Dolichol kinase (EC 2.7.1.108)(Transmembrane protein 15) [Source:UniProtKB/Swiss-Prot;Acc:Q9UPQ8]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 23406
     Entrez Gene : 22845
     UCSC : uc004bwr.2
     GeneCards : 23406
     RefSeq : NM_014908
     CCDS : CCDS6915.1
     Uniprot : Q9UPQ8
     Interpro : Q9UPQ8
     OMIM : 610746
     GeneTests : DOLK
     CGAP : DOLK
     PMID : 12975309

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  35403_at  -0.15  1.93e-1  2.83e-1  -0.24  1.87e-1  2.75e-1
 HG_U133A  204488_at  -0.01  8.13e-1  8.41e-1  -4.83  1.55e-124  2.15e-123
 HG_U133_Plus2  204488_at  0.14  2.65e-2  4.83e-2  0.25  1.39e-3  2.61e-3

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  204488_at  0.28  5.90e-2  7.22e-1  -0.20  1.08e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 35403_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 204488_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 204488_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
dolichol kinase hepatomas Cytidine 5'-triphosphate-dependent dolichol kinase and dolichol phosphatase activities and levels of dolichyl phosphate in microsomal fractions from highly differentiated human hepatomas. 2836054 Human
dolichol kinase hepatomas The dolichol monophosphatase activities in microsomal fractions from hepatomas and controls did not show any major differences, whereas the activity of the CTP-dependent dolichol kinase was increased in tumor microsomes. 2836054 Human
dolichol kinase tumor The dolichol monophosphatase activities in microsomal fractions from hepatomas and controls did not show any major differences, whereas the activity of the CTP-dependent dolichol kinase was increased in tumor microsomes. 2836054 Human
the dk gene tumour This series of experiments with the DTIC-treated L1210 tumour show the presence of an 'H-2D'-like antigen which resembles the Dk gene product/s of the H-2k haplotype. 6186748 Human
dk1 env gene Four of seven crossover points were identical; however, the env gene from UG1 was subtype D, but A1 in DK1. 18373434 Human

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