IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene SH3GLB2 Ensembl ENSG00000148341 Chromosome 9 Start 130810134 End 130830400
Description Endophilin-B2 (SH3 domain-containing GRB2-like protein B2) [Source:UniProtKB/Swiss-Prot;Acc:Q9NR46]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 10834
     Entrez Gene : 56904
     UCSC : uc004bwv.2
     GeneCards : 10834
     RefSeq : NM_020145
     CCDS : CCDS6916.1
     Uniprot : Q9NR46
     Interpro : Q9NR46
     OMIM : 609288
     GeneTests : SH3GLB2
     CGAP : SH3GLB2
     PMID : 11161816

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  218813_s_at  0.43  1.93e-6  4.83e-6  -1.54  1.01e-19  1.46e-19
 HG_U133_Plus2  218813_s_at  0.51  2.40e-3  5.72e-3  0.83  4.24e-6  1.14e-5
 HG_U133_Plus2  224432_at  -0.53  5.49e-4  1.50e-3  -0.59  3.52e-5  8.37e-5
 HG_U133_Plus2  224907_s_at  0.42  5.79e-5  1.92e-4  0.71  4.99e-8  1.73e-7
 Stanford  22968  0.31  2.56e-1  4.55e-1  -0.09  7.80e-1  8.96e-1
 Agilent_HS_21.6K  21327  -0.08  3.53e-2  1.14e-1  -0.08  1.11e-2  3.91e-2

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  218813_s_at  -0.19  6.78e-1  9.66e-1  -0.05  7.82e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U133A - 218813_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 218813_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 224432_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 224907_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 22968    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 21327    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
sh3glb2 metastases In humans, the Spas-1 ortholog SH3GLB2 has been reported to be overexpressed in prostate cancer metastases. 18303116 Human
sh3glb2 prostate cancer In humans, the Spas-1 ortholog SH3GLB2 has been reported to be overexpressed in prostate cancer metastases. 18303116 NA

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