IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene PPP2R4 Ensembl ENSG00000119383 Chromosome 9 Start 130913050 End 130951046
Description Serine/threonine-protein phosphatase 2A regulatory subunit B' (PP2A, subunit B', PR53 isoform)(Phosphotyrosyl phosphatase activator)(PTPA) [Source:UniProtKB/Swiss-Prot;Acc:Q15257]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 9308
     Entrez Gene : 5524
     UCSC : uc004bxl.1
     GeneCards : 9308
     RefSeq : NM_021131
     CCDS : CCDS6920.1
     Uniprot : Q9NNZ7
     Interpro : Q9NNZ7
     OMIM : 600756
     GeneTests : PPP2R4
     CGAP : PPP2R4
     PMID : 8530035

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  39127_f_at  -0.22  1.35e-2  3.03e-2  -0.10  3.39e-1  4.44e-1
 HG_U95  39128_r_at  0.31  3.28e-4  1.18e-3  0.49  3.82e-4  1.32e-3
 HG_U133A  206452_x_at  0.12  4.32e-2  6.07e-2  -1.49  2.10e-64  6.13e-64
 HG_U133A  208874_x_at  0.18  8.60e-4  1.58e-3  -1.03  2.18e-39  4.19e-39
 HG_U133A  216105_x_at  0.22  7.84e-5  1.65e-4  -5.43  2.78e-96  1.70e-95
 HG_U133_Plus2  206452_x_at  0.05  5.40e-1  6.24e-1  0.38  2.27e-4  4.81e-4
 HG_U133_Plus2  208874_x_at  0.12  1.51e-1  2.17e-1  0.43  2.39e-5  5.82e-5
 HG_U133_Plus2  216105_x_at  -0.01  9.38e-1  9.55e-1  0.34  1.03e-3  1.98e-3
 Agilent_HS_21.6K  2745  -0.00  9.56e-1  9.76e-1  0.01  7.96e-1  8.73e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  206452_x_at  -0.00  9.86e-1  9.99e-1  -0.01  9.56e-1  1.00e+0
 HG_U133A  208874_x_at  0.05  7.56e-1  9.75e-1  0.01  9.30e-1  1.00e+0
 HG_U133A  216105_x_at  -0.12  5.95e-1  9.52e-1  -0.06  6.60e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 39127_f_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 39128_r_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 206452_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 208874_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 216105_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 206452_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 208874_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 216105_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 2745    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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