IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene PRRX2 Ensembl ENSG00000167157 Chromosome 9 Start 131467741 End 131524770
Description Paired mesoderm homeobox protein 2 (Paired-related homeobox protein 2)(PRX-2) [Source:UniProtKB/Swiss-Prot;Acc:Q99811]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 21338
     Entrez Gene : 51450
     UCSC : uc004byh.2
     GeneCards : 21338
     RefSeq : NM_016307
     CCDS : CCDS6926.1
     Uniprot : Q99811
     Interpro : Q99811
     OMIM : 604675
     GeneTests : PRRX2
     CGAP : PRRX2
     PMID : 11063257

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  219729_at  0.09  4.41e-1  4.96e-1  2.66  2.66e-97  1.67e-96
 HG_U133_Plus2  219729_at  0.72  1.47e-4  4.51e-4  1.05  2.53e-6  7.02e-6
 Agilent_HS_21.6K  16644  0.09  4.75e-1  6.54e-1  0.34  2.08e-2  6.35e-2

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  219729_at  -0.80  2.32e-2  6.84e-1  0.32  3.56e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U133A - 219729_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 219729_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 16644    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
prrx2 therapy-related acute myeloid leukemia A new translocation t(9;11)(q34;p15) fuses NUP98 to a novel homeobox partner gene, PRRX2, in a therapy-related acute myeloid leukemia. 15496970 Human

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