IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene FNBP1 Ensembl ENSG00000187239 Chromosome 9 Start 131689287 End 131845267
Description Formin-binding protein 1 (Formin-binding protein 17)(hFBP17) [Source:UniProtKB/Swiss-Prot;Acc:Q96RU3]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 17069
     Entrez Gene : 23048
     UCSC : uc004byw.1
     GeneCards : 17069
     RefSeq : NM_015033
     CCDS : CCDS48040.1
     Uniprot : Q9NWD1
     Interpro : Q9NWD1
     OMIM : 606191
     GeneTests : FNBP1
     CGAP : FNBP1
     PMID : 9628581

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  40468_at  -0.69  9.96e-6  5.19e-5  -1.13  9.97e-8  7.65e-7
 HG_U133A  212288_at  -0.74  1.89e-26  2.32e-25  -4.62  1.16e-89  5.98e-89
 HG_U133A  213940_s_at  -0.37  3.44e-6  8.39e-6  0.40  7.90e-8  9.53e-8
 HG_U133_Plus2  212288_at  -0.83  2.38e-15  3.35e-14  -1.32  8.36e-20  1.13e-18
 HG_U133_Plus2  213940_s_at  -0.66  5.92e-14  7.10e-13  -0.77  3.62e-12  2.06e-11
 HG_U133_Plus2  230086_at  0.51  6.11e-3  1.32e-2  0.46  2.11e-2  3.24e-2
 HG_U133_Plus2  230389_at  -0.14  4.43e-1  5.32e-1  -0.87  1.88e-6  5.32e-6
 Agilent_HS_21.6K  14878  -0.05  1.86e-1  3.56e-1  -0.05  6.47e-2  1.50e-1
 Agilent_HS_21.6K  21191  -0.34  1.12e-4  1.32e-3  -0.46  2.17e-6  3.04e-5

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  212288_at  0.39  1.59e-1  8.13e-1  0.08  6.61e-1  1.00e+0
 HG_U133A  213940_s_at  -0.17  5.97e-1  9.52e-1  0.10  5.83e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 40468_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 212288_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 213940_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 212288_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 213940_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 230086_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 230389_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 14878    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 21191    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
fbp17 acute myeloid leukemia (aml) The t(9;11) has been described in patients with acute myeloid leukemia (AML), and two genes [AF9 (at 9p21) and FBP17 (at 9q34)] have been cloned as fusion partners of the MLL gene. 14978793 Human
fbp17 acute myelogeneous leukemia The human formin-binding protein 17 (FBP17) interacts with sorting nexin, SNX2, and is an MLL-fusion partner in acute myelogeneous leukemia. 11438682 Human
formin-binding protein 17 acute myelogeneous leukemia The human formin-binding protein 17 (FBP17) interacts with sorting nexin, SNX2, and is an MLL-fusion partner in acute myelogeneous leukemia. 11438682 Human

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