IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene EXOSC2 Ensembl ENSG00000130713 Chromosome 9 Start 132558988 End 132570073
Description Exosome complex exonuclease RRP4 (EC 3.1.13.-)(Ribosomal RNA-processing protein 4)(Exosome component 2) [Source:UniProtKB/Swiss-Prot;Acc:Q13868]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 17097
     Entrez Gene : 23404
     UCSC : uc004bzu.2
     GeneCards : 17097
     RefSeq : NM_014285
     CCDS : CCDS6935.1
     Uniprot : Q13868
     Interpro : Q13868
     OMIM : 602238
     GeneTests : EXOSC2
     CGAP : EXOSC2
     PMID : 8600032

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  32974_at  -0.09  5.91e-1  6.85e-1  0.48  1.42e-2  3.12e-2
 HG_U95  32975_g_at  0.22  2.62e-2  5.34e-2  0.75  7.56e-10  8.53e-9
 HG_U133A  209527_at  0.12  1.10e-1  1.43e-1  2.67  6.25e-95  3.67e-94
 HG_U133A  214507_s_at  0.95  1.18e-9  4.07e-9  -1.66  1.61e-31  2.75e-31
 HG_U133A  216117_at  -0.24  5.36e-2  7.41e-2  -0.70  4.56e-8  5.52e-8
 HG_U133_Plus2  209527_at  0.20  9.93e-3  2.03e-2  0.51  4.07e-9  1.61e-8
 HG_U133_Plus2  214507_s_at  -0.25  2.15e-1  2.94e-1  -0.27  2.17e-1  2.69e-1
 HG_U133_Plus2  216117_at  0.64  2.99e-4  8.66e-4  0.34  6.21e-2  8.73e-2
 Agilent_HS_21.6K  9326  -0.02  3.32e-1  5.21e-1  -0.01  7.68e-1  8.54e-1
 Agilent_HS_21.6K  10143  0.10  1.21e-2  5.27e-2  0.16  1.20e-4  9.30e-4

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  209527_at  0.83  6.80e-2  7.30e-1  0.27  1.13e-1  1.00e+0
 HG_U133A  214507_s_at  0.01  9.78e-1  9.99e-1  -0.23  3.88e-1  1.00e+0
 HG_U133A  216117_at  0.76  4.70e-2  7.08e-1  0.43  9.11e-2  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 32974_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 32975_g_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 209527_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 214507_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 216117_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 209527_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 214507_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 216117_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 9326    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 10143    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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