IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene UCK1 Ensembl ENSG00000130717 Chromosome 9 Start 133389009 End 133396476
Description Uridine-cytidine kinase 1 (UCK 1)(EC 2.7.1.48)(Uridine monophosphokinase 1)(Cytidine monophosphokinase 1) [Source:UniProtKB/Swiss-Prot;Acc:Q9HA47]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 14859
     Entrez Gene : 83549
     UCSC : uc004cay.2
     GeneCards : 14859
     RefSeq : NM_001135954
     CCDS : CCDS6944.1
     Uniprot : Q9HA47
     Interpro : Q9HA47
     OMIM : 609328
     GeneTests : UCK1
     CGAP : UCK1
     PMID : 11306702

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133_Plus2  223141_at  0.24  7.66e-4  2.04e-3  0.50  1.67e-8  6.13e-8
 HG_U133_Plus2  223142_s_at  0.06  6.93e-1  7.60e-1  0.33  4.82e-2  6.91e-2
 Stanford  2613  -0.10  7.51e-1  8.60e-1  -0.29  3.51e-1  5.90e-1
 Agilent_HS_21.6K  21203  -0.14  5.93e-4  5.00e-3  -0.11  1.47e-1  2.74e-1

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U133_Plus2 - 223141_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 223142_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 2613    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 21203    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
uck1 cancer Since the presence of a UCK family consisting of two members, UCK1 and UCK2, has recently been reported in human cells, we investigated the relation between expression of UCK1 and UCK2 at both the mRNA and protein levels and UCK activity (TAS-106 phosphor 12149149 Human
uck1 cancer Two members of human UCK, named UCK1 and UCK2, were cloned recently and UCK2 was reported to play a crucial role in activating anti-tumour pro-drugs in human cancer cells. 12876357 Human
uck1 tumor The UCK family consists of two members, UCK1 and UCK2, and both UCKs are expressed in many tumor cells. 15280220 Human

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