IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene MED27 Ensembl ENSG00000160563 Chromosome 9 Start 133725315 End 133945074
Description Mediator of RNA polymerase II transcription subunit 27 (Mediator complex subunit 27)(Cofactor required for Sp1 transcriptional activation subunit 8)(CRSP complex subunit 8)(Transcriptional coactivator CRSP34)(P37 TRAP/SMCC/PC2 subunit) [Source:UniProtKB/Swiss-Prot;Acc:Q6P2C8]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 2377
     Entrez Gene : 9442
     UCSC : uc004cbe.1
     GeneCards : 2377
     RefSeq : NM_004269
     CCDS : CCDS6945.1
     Uniprot : Q6P2C8
     Interpro : Q6P2C8
     OMIM : 605044
     GeneTests : MED27
     CGAP : MED27
     PMID : 9989412

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  215371_at  0.82  7.73e-11  2.97e-10  2.84  7.65e-54  1.85e-53
 HG_U133A  221598_s_at  0.14  3.67e-1  4.22e-1  -2.94  5.98e-33  1.04e-32
 HG_U133A  51176_at  0.04  4.99e-1  5.53e-1  -1.67  4.51e-61  1.24e-60
 HG_U133_Plus2  215371_at  -0.25  9.54e-2  1.47e-1  -0.50  4.57e-3  7.90e-3
 HG_U133_Plus2  221598_s_at  -0.76  3.53e-4  1.01e-3  -1.12  2.30e-5  5.62e-5
 HG_U133_Plus2  51176_at  0.15  4.56e-2  7.78e-2  0.61  2.28e-15  1.87e-14

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  215371_at  0.41  3.55e-1  8.91e-1  -0.25  3.69e-1  1.00e+0
 HG_U133A  221598_s_at  0.50  2.30e-1  8.46e-1  0.32  3.83e-1  1.00e+0
 HG_U133A  51176_at  0.16  3.90e-1  8.96e-1  0.12  4.17e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U133A - 215371_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 221598_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 51176_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 215371_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 221598_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 51176_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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