IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene SETX Ensembl ENSG00000107290 Chromosome 9 Start 134126648 End 134220193
Description Probable helicase senataxin (EC 3.6.1.-)(SEN1 homolog)(Amyotrophic lateral sclerosis 4 protein) [Source:UniProtKB/Swiss-Prot;Acc:Q7Z333]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 445
     Entrez Gene : 23064
     UCSC : uc004cbk.2
     GeneCards : 445
     RefSeq : NM_015046
     CCDS : CCDS6947.1
     Uniprot : Q7Z3J6
     Interpro : Q7Z3J6
     OMIM : 608465
     GeneTests : SETX
     CGAP : SETX
     PMID : 9497266

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  40083_at  -0.22  4.72e-4  1.62e-3  -0.19  2.83e-2  5.65e-2
 HG_U133A  201964_at  -0.51  2.19e-20  1.77e-19  -0.27  2.72e-5  3.14e-5
 HG_U133A  201965_s_at  -0.05  3.03e-1  3.56e-1  -1.42  1.22e-38  2.31e-38
 HG_U133_Plus2  201964_at  -0.35  7.52e-8  4.07e-7  -0.27  1.28e-3  2.42e-3
 HG_U133_Plus2  201965_s_at  -0.20  3.90e-4  1.10e-3  -0.12  1.05e-1  1.41e-1
 HG_U133_Plus2  232229_at  0.38  7.15e-4  1.91e-3  0.66  2.10e-10  9.69e-10

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  201964_at  0.30  1.30e-1  7.94e-1  -0.06  8.08e-1  1.00e+0
 HG_U133A  201965_s_at  -0.04  8.63e-1  9.89e-1  -0.04  7.80e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 40083_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 201964_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 201965_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 201964_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 201965_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 232229_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
senataxin smzl A comparison with the genes comprising the signature of other small B-cell lymphomas identified 3 genes whose expression distinguishes SMZL, namely ILF1, SENATAXIN, and CD40. 15914563 Human
senataxin small b-cell lymphomas A comparison with the genes comprising the signature of other small B-cell lymphomas identified 3 genes whose expression distinguishes SMZL, namely ILF1, SENATAXIN, and CD40. 15914563 Human

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