IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene TTF1 Ensembl ENSG00000125482 Chromosome 9 Start 134240756 End 134272042
Description Transcription termination factor 1 (TTF-1)(TTF-I)(RNA polymerase I termination factor) [Source:UniProtKB/Swiss-Prot;Acc:Q15361]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 12397
     Entrez Gene : 7270
     UCSC : uc004cbl.2
     GeneCards : 12397
     RefSeq : NM_007344
     CCDS : CCDS6948.1
     Uniprot : Q15361
     Interpro : Q15361
     OMIM : 600777
     GeneTests : TTF1
     CGAP : TTF1
     PMID : 7597036

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Experimental Evidence        (help)
Expression Sample Number Method Clinical information PubMed Reference
down 62/126(49%) IHCHistology(P<0.01)//Kaplan-Meier survival curve(P=0.0067) 12827614 Hum Pathol. 2003 Jun;34(6):597-604.

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  36478_at  -0.38  7.50e-2  1.30e-1  0.49  8.51e-2  1.43e-1
 HG_U133A  204771_s_at  0.04  5.28e-1  5.80e-1  -1.70  3.56e-46  7.61e-46
 HG_U133A  204772_s_at  0.18  3.53e-3  5.94e-3  3.18  4.54e-73  1.57e-72
 HG_U133_Plus2  204771_s_at  -0.03  7.12e-1  7.76e-1  -0.13  1.98e-1  2.48e-1
 HG_U133_Plus2  204772_s_at  -0.51  5.89e-7  2.76e-6  -0.45  1.10e-4  2.44e-4
 Stanford  15654  0.44  4.78e-2  1.51e-1  0.56  5.71e-2  1.87e-1
 Agilent_HS_21.6K  18138  0.08  6.70e-2  1.78e-1  0.13  1.81e-2  5.71e-2

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  204771_s_at  -0.15  4.01e-1  9.01e-1  0.17  2.37e-1  1.00e+0
 HG_U133A  204772_s_at  -0.00  9.97e-1  1.00e+0  0.17  2.89e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 36478_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 204771_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 204772_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 204771_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 204772_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 15654    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 18138    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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