IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene SURF1 Ensembl ENSG00000148290 Chromosome 9 Start 135208487 End 135213182
Description Surfeit locus protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q15526]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 11474
     Entrez Gene : 6834
     UCSC : uc004cdh.1
     GeneCards : 11474
     RefSeq : NM_003172
     CCDS : CCDS6966.1
     Uniprot : Q15526
     Interpro : Q15526
     OMIM : 185620
     GeneTests : SURF1
     CGAP : SURF1
     PMID : 8499913

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  35646_at  -0.20  5.68e-2  1.03e-1  -0.45  1.86e-3  5.34e-3
 HG_U133A  204295_at  0.20  2.01e-3  3.51e-3  -1.24  4.91e-36  8.97e-36
 HG_U133A  217646_at  0.17  9.67e-2  1.27e-1  -0.70  4.71e-9  5.82e-9
 HG_U133_Plus2  204295_at  0.00  9.99e-1  9.99e-1  -0.38  9.54e-6  2.45e-5
 HG_U133_Plus2  217646_at  -0.67  3.06e-3  7.11e-3  -1.65  1.06e-9  4.51e-9
 Stanford  3275  0.17  4.94e-1  6.76e-1  -0.16  4.51e-1  6.76e-1
 Agilent_HS_21.6K  6011  -0.15  1.00e-2  4.61e-2  -0.15  2.19e-2  6.61e-2

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  204295_at  0.35  1.02e-1  7.76e-1  -0.15  2.59e-1  1.00e+0
 HG_U133A  217646_at  0.04  8.92e-1  9.93e-1  -0.03  8.75e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 35646_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 204295_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 217646_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 204295_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 217646_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 3275    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 6011    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
surf1 esophageal cancer The sero-positive rates of antibodies against SURF1 (48%), LOC146223 (38%), HOOK2 (14%) and AGENCOURT-7565913 (14%) were significantly higher in esophageal cancer patients than in healthy controls. 15586227 Human
surf1 esophageal squamous-cell carcinoma A disease-specific humoral immune response against SURF1, LOC146223, HOOK2 or AGENCOURT-7565913 was observed in most patients with esophageal squamous cell carcinoma. 15586227 Human
surf1 esophageal squamous cell carcinoma A disease-specific humoral immune response against SURF1, LOC146223, HOOK2 or AGENCOURT-7565913 was observed in most patients with esophageal squamous cell carcinoma. 15586227 Human

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