IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene BRD3 Ensembl ENSG00000169925 Chromosome 9 Start 135887784 End 135923478
Description Bromodomain-containing protein 3 (RING3-like protein) [Source:UniProtKB/Swiss-Prot;Acc:Q15059]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 1104
     Entrez Gene : 8019
     UCSC : uc004cew.2
     GeneCards : 1104
     RefSeq : NM_007371
     CCDS : CCDS6980.1
     Uniprot : Q15059
     Interpro : Q15059
     OMIM : 601541
     GeneTests : BRD3
     CGAP : BRD3
     PMID : 7584044

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  31674_s_at  0.15  3.04e-1  4.09e-1  0.26  1.99e-1  2.89e-1
 HG_U95  37947_at  0.03  7.13e-1  7.88e-1  0.25  1.28e-2  2.86e-2
 HG_U95  41841_at  -0.22  6.09e-3  1.53e-2  0.06  5.39e-1  6.37e-1
 HG_U133A  203825_at  -0.16  1.31e-2  2.01e-2  -2.60  5.57e-83  2.43e-82
 HG_U133A  212547_at  -0.12  3.91e-3  6.53e-3  -2.58  2.60e-51  6.05e-51
 HG_U133_Plus2  1555028_at  -0.07  6.79e-1  7.48e-1  -0.13  5.53e-1  6.10e-1
 HG_U133_Plus2  203825_at  0.08  2.88e-1  3.74e-1  0.32  1.63e-3  3.03e-3
 HG_U133_Plus2  212547_at  0.22  8.98e-4  2.36e-3  0.51  4.65e-9  1.83e-8
 Stanford  21422  0.66  2.59e-3  2.68e-2  0.65  3.51e-2  1.33e-1
 Agilent_HS_21.6K  714  -0.30  2.87e-6  6.12e-5  -0.23  8.50e-4  4.74e-3
 Agilent_HS_21.6K  19993  0.03  2.50e-1  4.33e-1  0.07  7.87e-2  1.73e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  203825_at  -0.04  8.69e-1  9.90e-1  0.26  1.14e-1  1.00e+0
 HG_U133A  212547_at  -0.02  9.20e-1  9.95e-1  0.26  3.64e-2  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 31674_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 37947_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 41841_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 203825_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 212547_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 1555028_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 203825_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 212547_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 21422    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 714    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 19993    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
brd3 nasopharyngeal carcinoma [Expression of BRD7-interacting proteins,BRD2 and BRD3, in nasopharyngeal carcinoma tissues] BACKGROUND & OBJECTIVE: BRD7 is a novel gene tightly associated with nasopharyngeal carcinoma(NPC) cloned by cDNA representational difference analysis (cDNA RDA). 12600283 Human
brd3 bladder cancer A study of human BRD3, located on chromosome 9 at q34, a region susceptible to genomic rearrangement, showed an altered expression in 4 of 12 patients with bladder cancer, compared with adjacent noncancerous tissues. 16008511 Human
brd3 nasopharyngeal carcinoma(npc) [Expression of BRD7-interacting proteins,BRD2 and BRD3, in nasopharyngeal carcinoma tissues] BACKGROUND & OBJECTIVE: BRD7 is a novel gene tightly associated with nasopharyngeal carcinoma(NPC) cloned by cDNA representational difference analysis (cDNA RDA). 12600283 Human
brd3 npc This study was designed to further identify the interactions of BRD2 and BRD3 with BRD7 respectively and to investigate the expression and action pattern of BRD2 and BRD3 in NPC. 12600283 Human
brd3 npc Besides,reverse transcription-polymerase chain reaction (RT- PCR) was used to examine the expression of BRD2 and BRD3 genes in normal nasopharyngeal epithelium and NPC biopsies, and to detect the effect of re-expression of BRD7 gene on the expression of B 12600283 Human
brd3 npc Down-expression or loss of BRD2 and BRD3 genes were detectable in NPC biopsies. 12600283 Human
orfx oncogene The cause of the QTL effect is a single gene, ORFX, that is expressed early in floral development, controls carpel cell number, and has a sequence suggesting structural similarity to the human oncogene c-H-ras p21. 10884229 Human

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