IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene COL5A1 Ensembl ENSG00000130635 Chromosome 9 Start 136673473 End 136876510
Description Collagen alpha-1(V) chain Precursor [Source:UniProtKB/Swiss-Prot;Acc:P20908]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 2209
     Entrez Gene : 1289
     UCSC : uc004cfe.2
     GeneCards : 2209
     RefSeq : NM_000093
     CCDS : CCDS6982.1
     Uniprot : P20908
     Interpro : P20908
     OMIM : 120215
     GeneTests : COL5A1
     CGAP : COL5A1
     PMID : 1572660

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  203325_s_at  1.05  1.19e-14  6.24e-14  -0.02  8.80e-1  8.84e-1
 HG_U133A  212488_at  1.35  4.56e-27  5.80e-26  3.22  1.30e-101  9.21e-101
 HG_U133A  212489_at  1.38  4.72e-28  6.41e-27  2.80  3.88e-81  1.61e-80
 HG_U133_Plus2  1556138_a_at  -0.37  2.07e-2  3.90e-2  -0.39  1.32e-2  2.10e-2
 HG_U133_Plus2  203325_s_at  0.88  5.55e-8  3.06e-7  1.24  3.33e-12  1.91e-11
 HG_U133_Plus2  212488_at  1.31  6.73e-15  9.03e-14  1.78  1.27e-20  1.89e-19
 HG_U133_Plus2  212489_at  1.52  2.47e-16  3.89e-15  2.20  1.47e-25  3.86e-24
 Stanford  6093  0.02  9.65e-1  9.81e-1  -0.69  1.61e-1  3.71e-1
 Agilent_HS_21.6K  5772  -0.03  7.59e-1  8.61e-1  0.01  9.46e-1  9.69e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  203325_s_at  -0.09  8.50e-1  9.88e-1  -0.26  4.77e-1  1.00e+0
 HG_U133A  212488_at  -0.05  9.16e-1  9.95e-1  -0.20  5.19e-1  1.00e+0
 HG_U133A  212489_at  -0.06  8.90e-1  9.93e-1  -0.21  4.99e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U133A - 203325_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 212488_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 212489_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 1556138_a_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 203325_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 212488_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 212489_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 6093    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 5772    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
col5a1 hereditary osteo-onychodysplasia In addition, these studies place COL5A1 near the locus for the genetic disorder, nail-patella syndrome (hereditary osteo-onychodysplasia), which also maps to 9q34. 1572660 Human
col5a1 metastasis Gene and protein expression patterns resulting from caffeine treatment showed that metastasis suppression may be associated with up-regulation the mRNA expression of multiple extracellular matrix genes, including Fbln1, Bgn, Sparc, Fbn1, Loxl1, Colla1, Co 16035617 Human
col5a1 hypomelanosis of ito A translocation interrupts the COL5A1 gene in a patient with Ehlers-Danlos syndrome and hypomelanosis of Ito. 8673139 Human
col5a1 hypomelanosis of ito Here, we describe a balanced translocation between chromosome 9 and an X chromosome that disrupts the minor fibrillar collagen type V gene COL5A1 in a patient with both EDS type I and hypomelanosis of Ito. 8673139 Human

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