IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene KIAA0649 Ensembl ENSG00000196422 Chromosome 9 Start 137510746 End 137520560
Description Protein KIAA0649 [Source:UniProtKB/Swiss-Prot;Acc:Q5T8A7]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 29089
     Entrez Gene : 9858
     UCSC : uc004cfr.1
     GeneCards : 29089
     RefSeq : NM_014811
     CCDS : CCDS6988.1
     Uniprot : Q5T8A7
     Interpro : Q5T8A7
     GeneTests : KIAA0649
     CGAP : KIAA0649
     PMID : 9734811

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  39580_at  -0.48  2.19e-2  4.56e-2  -0.70  1.49e-2  3.26e-2
 HG_U133A  203955_at  -0.15  2.52e-2  3.70e-2  2.15  3.10e-79  1.23e-78
 HG_U133_Plus2  203955_at  -0.10  1.78e-1  2.50e-1  -0.37  1.05e-3  2.01e-3
 Stanford  13929  0.40  1.62e-1  3.41e-1  0.10  7.79e-1  8.96e-1
 Agilent_HS_21.6K  15333  -0.08  6.13e-2  1.68e-1  -0.12  1.40e-2  4.68e-2

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  203955_at  -0.36  1.01e-1  7.76e-1  0.23  3.97e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 39580_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 203955_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 203955_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 13929    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 15333    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
kiaa0649 tumor Moreover, KIAA0649 exogenous expression in NIH3T3 fibroblasts caused tumor development in nude mice. 16053918 Mouse
kiaa0649 oncogenic KIAA0649, a 1A6/DRIM-interacting protein with the oncogenic potential. 16053918 Human
kiaa0649 oncogenic We have also demonstrated that KIAA0649 has oncogenic characteristics: it enhances colony formation, allows anchorage-independent growth. 16053918 Mouse

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