IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene LCN1 Ensembl ENSG00000160349 Chromosome 9 Start 137553105 End 137558199
Description Lipocalin-1 Precursor (Von Ebner gland protein)(VEG protein)(Tear prealbumin)(TP)(Tear lipocalin)(Tlc) [Source:UniProtKB/Swiss-Prot;Acc:P31025]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 6525
     Entrez Gene : 3933
     UCSC : uc004cga.1
     GeneCards : 6525
     RefSeq : NM_002297
     CCDS : CCDS6991.1
     Uniprot : P31025
     Interpro : P31025
     OMIM : 151675
     GeneTests : LCN1
     CGAP : LCN1
     PMID : 8276406

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  34102_at  0.31  1.82e-2  3.91e-2  -0.08  6.39e-1  7.27e-1
 HG_U133A  207930_at  -0.08  4.31e-1  4.86e-1  -3.14  4.59e-79  1.82e-78
 HG_U133_Plus2  207930_at  0.46  1.90e-2  3.62e-2  0.74  1.02e-3  1.95e-3

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  207930_at  -0.09  8.47e-1  9.88e-1  -0.23  1.66e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 34102_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 207930_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 207930_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
the tp gene tumor We determined the level of STAT1alpha, an IFN-inducible transcription factor of the TP gene, and found that it was low in low TP expressing tumor cells and markedly increased to about 4 fold by IFN, almost reaching the level in high TP expressing cells wh 12359357 Human

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