IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene EGFL7 Ensembl ENSG00000172889 Chromosome 9 Start 138673129 End 138686951
Description EGF-like domain-containing protein 7 Precursor (Multiple EGF-like domain protein 7)(Multiple epidermal growth factor-like domain protein 7)(Vascular endothelial statin)(VE-statin)(NOTCH4-like protein)(ZNEU1) [Source:UniProtKB/Swiss-Prot;Acc:Q9UHF1]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :
     HGNC : 20594
     Entrez Gene : 51162
     UCSC : uc004cif.2
     GeneCards : 20594
     RefSeq : NM_016215
     CCDS : CCDS7002.1
     Uniprot : Q9UHF1
     Interpro : Q9UHF1
     OMIM : 608582
     GeneTests : EGFL7
     CGAP : EGFL7

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  218825_at  -1.50  4.91e-52  2.68e-50  0.18  6.16e-2  6.54e-2
 HG_U133_Plus2  218825_at  -0.99  2.79e-10  2.10e-9  -1.20  1.07e-10  5.14e-10
 Agilent_HS_21.6K  19769  -0.33  2.97e-13  4.15e-11  -0.37  4.67e-15  1.06e-12

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  218825_at  0.08  8.23e-1  9.84e-1  -0.08  7.59e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U133A - 218825_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 218825_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 19769    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
egfl7 colon cancer We assessed in 110 colon cancer patients the levels of miR-17-5p, miR-106a, miR-126, E2F1, and EGFL7 by quantitative real-time RT-PCR and loss of heterozygosity (LOH) in the TP53 region. 18521848 Human
egfl7 pathological tumor Altered expression of miR-17-5p, miR-106a, and EGFL7 was associated with pathological tumor features of poor prognosis. 18521848 Human
egfl7 tumor No correlation was found between miR-126 expression and its host gene levels, EGFL7. miR-106a deregulation was revealed as a marker of DFS and OS independent of tumor stage. 18521848 Human

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