IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene DPP7 Ensembl ENSG00000176978 Chromosome 9 Start 139124814 End 139129016
Description Dipeptidyl-peptidase 2 Precursor (EC 3.4.14.2)(Dipeptidyl-peptidase II)(DPP II)(Dipeptidyl aminopeptidase II)(Quiescent cell proline dipeptidase)(Dipeptidyl peptidase 7) [Source:UniProtKB/Swiss-Prot;Acc:Q9UHL4]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 14892
     Entrez Gene : 29952
     UCSC : uc004clh.2
     GeneCards : 14892
     RefSeq : NM_013379
     CCDS : CCDS7030.1
     Uniprot : Q9UHL4
     Interpro : Q9UHL4
     OMIM : 610537
     GeneTests : DPP7
     CGAP : DPP7
     PMID : 10477574

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133_Plus2  224814_at  -0.10  3.27e-1  4.16e-1  -0.15  1.84e-1  2.33e-1
 HG_U133_Plus2  238012_at  0.32  1.41e-3  3.53e-3  0.37  4.44e-3  7.69e-3
 HG_U133_Plus2  241973_x_at  0.55  2.45e-4  7.22e-4  1.16  2.88e-10  1.31e-9
 Stanford  491  0.10  7.02e-1  8.28e-1  -0.01  9.72e-1  9.88e-1
 Stanford  21013  0.44  1.81e-1  3.65e-1  0.34  3.47e-1  5.86e-1
 Agilent_HS_21.6K  3613  -0.19  1.64e-5  2.64e-4  -0.18  2.77e-4  1.87e-3
 Agilent_HS_21.6K  4064  -0.23  6.19e-7  1.62e-5  -0.22  5.52e-6  6.78e-5
 Agilent_HS_21.6K  10337  -0.23  3.50e-7  9.90e-6  -0.22  2.45e-5  2.43e-4

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U133_Plus2 - 224814_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 238012_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 241973_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 491    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 21013    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 3613    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 4064    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 10337    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
dpp-ii squamous-cell lung carcinoma (sqclc) In the present work we studied the levels of activities of dipeptidyl-peptidase I (or cathepsin C, DPP-I) and dipeptidyl-peptidase II (DPP-II) and examined their isoelectric focusing profiles in matched pairs of human squamous cell lung carcinoma (SQCLC) 8841504 Human
dpp-ii tumors The isoelectric focusing profile of several DPP-II forms in SQCLCs and the lungs was similar and the single major DPP-II isoform revealed in the tumors and lungs showed a pIapp of 5.3-5.2. 8841504 Human
dpp2 cll As CLL malignant cells are arrested in G(0), we investigated whether Dipeptidyl Peptidase 2 (DPP2), a serine protease that plays a key role in keeping cells in the quiescent state, is involved in cell-cycle control in CLL. 15686454 Human

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