IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene NDOR1 Ensembl ENSG00000188566 Chromosome 9 Start 139220004 End 139231281
Description NADPH-dependent diflavin oxidoreductase 1 (EC 1.6.-.-)(Novel reductase 1)(NADPH-dependent FMN and FAD containing oxidoreductase) [Source:UniProtKB/Swiss-Prot;Acc:Q9UHB4]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 29838
     Entrez Gene : 27158
     UCSC : uc004clw.2
     GeneCards : 29838
     RefSeq : NM_001144026
     CCDS : CCDS7036.1
     Uniprot : Q9UHB4
     Interpro : Q9UHB4
     OMIM : 606073
     GeneTests : NDOR1
     CGAP : NDOR1
     PMID : 10625700

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  219899_x_at  -0.42  1.51e-4  3.07e-4  2.62  1.80e-53  4.33e-53
 HG_U133_Plus2  219899_x_at  0.31  5.65e-2  9.36e-2  0.27  1.87e-1  2.36e-1
 HG_U133_Plus2  227739_at  0.24  1.30e-1  1.92e-1  0.42  1.32e-2  2.11e-2
 HG_U133_Plus2  234318_x_at  0.27  4.86e-4  1.35e-3  0.33  2.31e-4  4.89e-4
 HG_U133_Plus2  234935_at  -0.14  4.03e-1  4.93e-1  -0.31  8.17e-2  1.12e-1
 Agilent_HS_21.6K  20804  0.13  2.18e-1  3.95e-1  0.12  2.40e-1  3.91e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  219899_x_at  0.41  4.29e-1  9.12e-1  -0.18  5.54e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U133A - 219899_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 219899_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 227739_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 234318_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 234935_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 20804    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
nr1 cancer Immunoblot analysis of fractionated MCF7 cells with antibodies to recombinant NR1 showed that the enzyme is cytoplasmic and highly expressed in a panel of human cancer cell lines, thus indicating that this novel reductase may play a role in the metabolic 10625700 Human
ndor1 cancer This will help define the structure and function of NDOR1 and its relationship to cancer and other diseases. 15900210 Human

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