IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene MRPL41 Ensembl ENSG00000182154 Chromosome 9 Start 139566165 End 139566827
Description 39S ribosomal protein L41, mitochondrial Precursor (L41mt)(MRP-L41)(39S ribosomal protein L27 homolog)(MRP-L27 homolog)(Bcl-2-interacting mitochondrial ribosomal protein L41)(Cell proliferation-inducing gene 3 protein) [Source:UniProtKB/Swiss-Prot;Acc:Q8IXM3]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 14492
     Entrez Gene : 64975
     UCSC : uc004cnh.3
     GeneCards : 14492
     RefSeq : NM_032477
     CCDS : CCDS7046.1
     Uniprot : Q8IXM3
     Interpro : Q8IXM3
     OMIM : 611846
     GeneTests : MRPL41
     CGAP : MRPL41
     PMID : 11543634

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  221936_x_at  -0.37  3.89e-4  7.49e-4  -0.44  1.66e-4  1.88e-4
 HG_U133_Plus2  221936_x_at  -0.18  2.77e-1  3.62e-1  0.10  6.01e-1  6.55e-1
 HG_U133_Plus2  225423_x_at  -0.09  6.51e-1  7.23e-1  0.15  4.65e-1  5.26e-1
 HG_U133_Plus2  225425_s_at  0.00  9.94e-1  9.95e-1  -0.01  8.75e-1  8.98e-1
 HG_U133_Plus2  227186_s_at  0.39  7.64e-8  4.13e-7  0.36  4.25e-4  8.66e-4
 HG_U133_Plus2  230034_x_at  -0.22  2.08e-1  2.86e-1  -0.09  6.15e-1  6.67e-1
 Agilent_HS_21.6K  8468  0.11  4.88e-2  1.43e-1  0.16  2.55e-2  7.42e-2

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  221936_x_at  0.05  8.93e-1  9.93e-1  0.27  2.15e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U133A - 221936_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 221936_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 225423_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 225425_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 227186_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 230034_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 8468    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
mrpl41 tumor An analysis of MRPL41 expression in paired normal and tumor tissues revealed lower expression in tumor tissue. 16024796 Mouse
mrpl41 tumor Ectopic MRPL41 expression resulted in inhibition of the growth of cancer cells in tissue culture and tumor growth in nude mice. 16024796 Mouse
mrpl41 cancer Ectopic MRPL41 expression resulted in inhibition of the growth of cancer cells in tissue culture and tumor growth in nude mice. 16024796 Mouse
pig3 lung carcinoma Over expression of wild-type, but not deletion mutant, SSRP1 remarkably enhanced p63gamma-dependent luciferase activity, G1 arrest, apoptosis and expression of endogenous PIG3, p21(Waf1/cip1) and MDM2 in human p53-deficient lung carcinoma H1299 cells and 12374749 Human
pig3 acute myeloid leukemias Loss of heterozygosity of the polymorphic PIG3 microsatellite with low frequency in de novo acute myeloid leukemias. 15085148 Human

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