IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene CACNA1B Ensembl ENSG00000148408 Chromosome 9 Start 139892062 End 140138897
Description Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage-gated calcium channel subunit alpha Cav2.2)(Calcium channel, L type, alpha-1 polypeptide isoform 5)(Brain calcium channel III)(BIII) [Source:UniProtKB/Swiss-Prot;Acc:Q00975]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 1389
     Entrez Gene : 774
     UCSC : uc004cog.2
     GeneCards : 1389
     RefSeq : NM_000718
     Uniprot : Q00975
     Interpro : Q00975
     OMIM : 601012
     GeneTests : CACNA1B
     CGAP : CACNA1B
     PMID : 8825650

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  33960_s_at  0.45  3.74e-8  3.33e-7  0.47  5.27e-4  1.76e-3
 HG_U133A  207162_s_at  0.30  2.13e-3  3.70e-3  1.45  8.12e-24  1.25e-23
 HG_U133_Plus2  207162_s_at  0.27  3.70e-2  6.46e-2  0.98  1.44e-6  4.13e-6
 HG_U133_Plus2  235781_at  0.87  4.95e-5  1.66e-4  2.75  7.72e-21  1.17e-19
 Agilent_HS_21.6K  7092  -0.17  2.53e-2  9.01e-2  -0.13  4.31e-2  1.10e-1
 Agilent_HS_21.6K  8438  0.03  3.62e-1  5.50e-1  0.04  1.74e-1  3.11e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  207162_s_at  -0.54  1.98e-1  8.29e-1  -0.11  7.44e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 33960_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 207162_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 207162_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 235781_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 7092    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 8438    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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