IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene BNC2 Ensembl ENSG00000173068 Chromosome 9 Start 16399501 End 16860786
Description Zinc finger protein basonuclin-2 [Source:UniProtKB/Swiss-Prot;Acc:Q6ZN30]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 30988
     Entrez Gene : 54796
     UCSC : uc003zml.2
     GeneCards : 30988
     RefSeq : NM_017637
     CCDS : CCDS6482.2
     Uniprot : Q6ZN30
     Interpro : Q6ZN30
     OMIM : 608669
     GeneTests : BNC2
     CGAP : BNC2
     PMID : 14702039

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  220272_at  -0.78  1.06e-24  1.15e-23  -1.08  2.00e-20  2.93e-20
 HG_U133_Plus2  220272_at  -0.12  2.80e-1  3.66e-1  0.18  7.52e-2  1.04e-1
 HG_U133_Plus2  229942_at  -0.25  8.09e-2  1.28e-1  -0.19  2.41e-1  2.96e-1
 HG_U133_Plus2  230722_at  -0.57  2.13e-8  1.25e-7  -0.66  6.20e-8  2.12e-7
 HG_U133_Plus2  235723_at  -0.82  1.12e-6  5.02e-6  -0.75  7.80e-5  1.77e-4
 HG_U133_Plus2  238478_at  -0.51  3.91e-6  1.60e-5  -0.46  8.93e-6  2.31e-5
 HG_U133_Plus2  243445_at  0.12  5.40e-1  6.24e-1  0.94  5.35e-7  1.63e-6
 Agilent_HS_21.6K  1669  0.02  5.88e-1  7.43e-1  0.02  5.06e-1  6.53e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  220272_at  0.04  8.43e-1  9.87e-1  0.21  1.98e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U133A - 220272_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 220272_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 229942_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 230722_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 235723_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 238478_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 243445_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 1669    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
basonuclin2 bcc As expected, members of the Wnt and hedgehog pathways were found to be significantly different between BCC and normal specimens, as were many previously undescribed changes in gene expression between normal and BCC specimens, including basonuclin2 and mrp 17173689 Human

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