IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene RFX3 Ensembl ENSG00000080298 Chromosome 9 Start 3214649 End 3515983
Description Transcription factor RFX3 (Regulatory factor X 3) [Source:UniProtKB/Swiss-Prot;Acc:P48380]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 9984
     Entrez Gene : 5991
     UCSC : uc003zhr.2
     GeneCards : 9984
     RefSeq : NM_002919
     CCDS : CCDS6449.1
     Uniprot : P48380
     Interpro : P48380
     OMIM : 601337
     GeneTests : RFX3
     CGAP : RFX3
     PMID : 8289803

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  31929_at  0.65  4.45e-5  1.98e-4  0.83  9.18e-4  2.87e-3
 HG_U133A  207234_at  -0.30  3.64e-4  7.05e-4  -0.87  5.87e-8  7.09e-8
 HG_U133_Plus2  207234_at  -0.22  8.19e-2  1.29e-1  0.43  9.97e-4  1.92e-3
 HG_U133_Plus2  238810_at  -0.21  3.25e-1  4.14e-1  -0.15  5.06e-1  5.66e-1
 Agilent_HS_21.6K  1989  -0.05  4.38e-1  6.21e-1  -0.03  5.92e-1  7.24e-1
 Agilent_HS_21.6K  20703  -0.04  4.55e-1  6.36e-1  -0.04  5.34e-1  6.77e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  207234_at  -0.63  4.17e-2  7.08e-1  0.22  3.68e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 31929_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 207234_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 207234_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 238810_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 1989    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 20703    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
rfx3 chordoid glioma PTPRs, classified with chordoid glioma and separately from ependymomas, showed high expression of SPEDF, KRT18, and genes encoding proteins reported to be expressed in the subcommissural organ, namely ZFH4, RFX3, TTR, and CGRP. 16825954 Human

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